ENSMUSG00000097583 (6430590A07Rik)

mus musculus

RIKEN cDNA 6430590A07 gene

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Mus musculus
Organism part
Showing 25 experiments:
Created with Highcharts 6.2.0arcuate nucleus of hypothalamusbrown adipose tissuecaudal brain neural epitheliumcerebellumdentate gyrus of hippocampal formationdorsal raphe nucleusfloor platehearthypothalamusinguinal fat padlateral nasal prominencelivermandibular archmedial nasal prominencemesodermnon-floor plate neural epitheliumolfactory epitheliumpreoptic areaspleensubventricular zonethymuswhite adipose tissue
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9 in 3 strains - C57BL/6
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14 - embryonic day 10.5
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9 in 3 strains - DBA/2J
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9 in 3 strains - CD1
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Mammalian Kaessmann
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Vertebrates
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4
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14 - embryonic day 9.5
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14 - embryonic day 8.5
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Fat and muscle
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6
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Sun et al., 2020 - Organism part
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Gregg et al - C57BL/6J
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Gregg et al - (CAST/EiJ X C57BL/6J)F1
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9
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3 Soumillon et al
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Gregg et al - CAST/EiJ
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Gregg et al - (C57BL/6J X CAST/EiJ)F1
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4 Bonthuis et al - C57BL/6J
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4 Bonthuis et al - (CastEiJ X …
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4 Bonthuis et al - (C57BL/6J X …
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Developing gut
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4 Bonthuis et al - Idaho derived wild …
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4 Bonthuis et al - CastEiJ
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Proteomics
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Transcriptomics
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-4.4
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Display log2-fold change
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Log2-fold changeSpeciesGene nameComparisonExperimental variablesExperiment name
Adjusted p-valueLog2-fold change
1.0494 × 10-12-4.4
6430590A07Rik'AZD5069; 100 milligram per kilogram' vs 'none'compoundRNA-seq to investigate differentially expressed genes in KPC mouse PDAC treated with CSF-1R small molecule inhibitor AZD7507 and/or the CXCR2 small molecule inhibitor AZD5069
Adjusted p-valueLog2-fold change
1.3751 × 10-3-4.2
6430590A07Rik'pabpn1l -/-' vs 'wild type genotype' in 'zygote'genotype, organism partRNA-seq of oocytes and zygotes from pabpn1l ko and wt female mice
Adjusted p-valueLog2-fold change
2.2528 × 10-10-3.9
6430590A07Rik'AZD7507; AZD5069 (at same dosage); 100 milligram per kilogram' vs 'none'compoundRNA-seq to investigate differentially expressed genes in KPC mouse PDAC treated with CSF-1R small molecule inhibitor AZD7507 and/or the CXCR2 small molecule inhibitor AZD5069
Adjusted p-valueLog2-fold change
1.0539 × 10-24-3.5
6430590A07Rik'undifferentiated' vs 'differentiated; rosiglitazone' in 'A/J'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
5.2326 × 10-21-3.4
6430590A07Rik'undifferentiated' vs 'differentiated; rosiglitazone' in '129S6sv/ev'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
2.6796 × 10-9-2.8
6430590A07Rik'undifferentiated' vs 'differentiated; rosiglitazone' in 'AKR/J'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
5.2933 × 10-13-2.7
6430590A07Rik'undifferentiated' vs 'differentiated; rosiglitazone' in 'SWR/J'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
4.8815 × 10-3-2.6
6430590A07Rik'PTEN null' vs 'wild type genotype'genotypeRNA seq of prostate gland from WT, PTEN pc -/- and PTEN pc-/-;P53 -/- mice
Adjusted p-valueLog2-fold change
1.1861 × 10-16-2.5
6430590A07Rik'undifferentiated' vs 'differentiated; rosiglitazone' in 'F1.129xB6'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
5.6675 × 10-13-2.5
6430590A07Rik'undifferentiated' vs 'differentiated; rosiglitazone' in 'C57BL/6J'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
2.4467 × 10-4-2.5
6430590A07Rik'chemical hypoxia' vs 'control'growth conditionComparison of gene expression in whole blood of mice subjected to chemical hypoxia in vivo.
Adjusted p-valueLog2-fold change
3.0602 × 10-7-2.3
6430590A07Rik'lipopolysaccharide; 10 nanogram per milliliter' vs 'none' in 'Hoxb8-FL; MEF2A knockout'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
7.0267 × 10-3-2.3
6430590A07Rik'Alb-Cre-ERT2 / Cnot1 flox/flox' vs 'Cnot1 flox/flox' in 'none'compound, genotype, timeRNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice
Adjusted p-valueLog2-fold change
6.2698 × 10-13-2.2
6430590A07Rik'undifferentiated' vs 'differentiated; rosiglitazone' in 'F1.B6x129'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
9.1003 × 10-3-2.2
6430590A07Rik'extracellular vesicle; MET cell culture medium' vs 'none'sampling site, stimulusCellular and extracellular vesicle RNA sequence for E-cadherin-RFP EMT reporter system expressing mouse breast cancer cell line Py2T during EMT/MET
Adjusted p-valueLog2-fold change
2.6982 × 10-2-2.2
6430590A07Rik'PTEN null, P53-/-' vs 'wild type genotype'genotypeRNA seq of prostate gland from WT, PTEN pc -/- and PTEN pc-/-;P53 -/- mice
Adjusted p-valueLog2-fold change
1.4811 × 10-8-2.1
6430590A07Rik'myeloid lineage restricted progenitor cell' vs 'long term hematopoietic stem cell' in 'Elp3fl/fl'cell type, genotypeRNA-seq of long-term hematopoietic stem cells and myeloid progenitors of control mice or mice conditionally deficient for Trp53 or Elp3 or both genes in the hematopoietic system
Adjusted p-valueLog2-fold change
4.2604 × 10-3-2.1
6430590A07Rik'clear cell sarcoma; TATCre' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
1.8971 × 10-52
6430590A07Rik'cycloheximide and 100 unit per milliliter interferon gamma' vs 'DMSO'compoundDissecting primary (translation independent) from secondary (translation dependent) IFN-mediated differential gene expression
Adjusted p-valueLog2-fold change
1.3459 × 10-3-2
6430590A07Rik'AhCre Cited1 knockout' vs 'control'genotypeCited-1 deficiency suppresses intestinal tumorigenesis through the repression of the Wnt pathway- evidence for the just right model of Wnt mediated tumorigenesis
Adjusted p-valueLog2-fold change
8.0379 × 10-4-1.9
6430590A07Rik'AhCre Apc Floxed Cited1 knockout' vs 'control'genotypeCited-1 deficiency suppresses intestinal tumorigenesis through the repression of the Wnt pathway- evidence for the just right model of Wnt mediated tumorigenesis
Adjusted p-valueLog2-fold change
3.4112 × 10-21.9
6430590A07Rik'heat-shocked at 42 degreeC' vs 'grown at 33 degreeC' in 'HdhQ111 knock-in'genotype, growth conditionTranscription profiling by array of mouse wild type and Htt mutant striatal cells upon heat shock
Adjusted p-valueLog2-fold change
4.0118 × 10-11-1.8
6430590A07Rik'α-GalCer; 2 microgram' vs 'none' in 'Cd1d homozyous knockout'compound, genotypeCD1d-dependent immune suppression mediated by regulatory B cells through modulations of iNKT cells
Adjusted p-valueLog2-fold change
3.1569 × 10-3-1.8
6430590A07Rik'fear conditioning' vs 'none'stimulusGene-expression changes in neurons active during contextual fear conditioning compared to controls left in the homecage
Adjusted p-valueLog2-fold change
2.0046 × 10-31.7
6430590A07Rik'reduced expression of miR-25' vs 'wild type'phenotypeTranscription profiling by high throughput sequencing of wild type and miR-25 agomir or antagomir treated mice
Adjusted p-valueLog2-fold change
2.2768 × 10-3-1.7
6430590A07Rik'PF-04691502–resistant cell; 1 micromolar; PF-04691502' vs 'parental AKP cell; dimethyl sulfoxide'compound, phenotypeResistance to PI3K/mTOR inhibitor PF-04691502 in KRAS mutant colorectal cancer models reveals a sensitivity to combination with EGFR inhibition
Adjusted p-valueLog2-fold change
2.3749 × 10-41.6
6430590A07Rik'cycloheximide' vs 'DMSO'compoundDissecting primary (translation independent) from secondary (translation dependent) IFN-mediated differential gene expression
Adjusted p-valueLog2-fold change
1.2593 × 10-2-1.6
6430590A07Rik'osteosarcoma' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
4.8349 × 10-2-1.6
6430590A07Rik'adipose tissue specific Cnot1 knockout' vs 'wild type phenotype' in 'brown adipose tissue'organism part, phenotypeRNA-seq to identify the role of mRNA decay in mouse adipose tissues
Adjusted p-valueLog2-fold change
2.3899 × 10-41.5
6430590A07Rik'cycloheximide and 100 unit per milliliter interferon alpha' vs 'DMSO'compoundDissecting primary (translation independent) from secondary (translation dependent) IFN-mediated differential gene expression
Adjusted p-valueLog2-fold change
2.996 × 10-3-1.5
6430590A07Rik'Lymphocytic choriomeningitis mammarenavirus' vs 'none' in 'TRAIL homozygous knock out'genotype, infectComparison of Trail+/+ versus Trail-/- splenic NK cells from naïve and LCMV-infected mice
Adjusted p-valueLog2-fold change
3.8699 × 10-2-1.5
6430590A07Rik'germ free C57BL/6' vs 'specific pathogen free C57BL/6' in 'wild type genotype'genotype, strainRNA sequencing of primary isolated unstimulated murine splenic cDC from specific pathogen free (SPF), Germ Free (GF) and Interferon alpha/beta receptor 1 (Ifnar) knock out mice.
Adjusted p-valueLog2-fold change
1.1338 × 10-41.4
6430590A07Rik'artesunate and chloroquine (at same dosage); 30 milligram per kilogram' at '14 day' vs 'none' at '7 day' in 'Plasmodium berghei ANKA'compound, infect, sampling time pointRNA-seq analysis of anti-malarial drug chemotherapy of murine experimental Cerebral Malaria (ECM)
Adjusted p-valueLog2-fold change
2.2935 × 10-4-1.4
6430590A07Rik'Plasmodium berghei ANKA' at '7 day' vs 'none' at '0 day' in 'none'compound, infect, sampling time pointRNA-seq analysis of anti-malarial drug chemotherapy of murine experimental Cerebral Malaria (ECM)
Adjusted p-valueLog2-fold change
3.9748 × 10-41.4
6430590A07Rik'artesunate and chloroquine (at same dosage); 30 milligram per kilogram' at '30 day' vs 'none' at '7 day' in 'Plasmodium berghei ANKA'compound, infect, sampling time pointRNA-seq analysis of anti-malarial drug chemotherapy of murine experimental Cerebral Malaria (ECM)
Adjusted p-valueLog2-fold change
2.1014 × 10-31.4
6430590A07Rik'neurogenin-3-expressing endocrine progenitor cell' vs 'neurogenin-3-lacking pancreatic progenitor cell' at 'embryonic day 15.5'cell type, developmental stageTranscription profiling by high throughput sequencing of murine beta cells at key stages of maturation
Adjusted p-valueLog2-fold change
4.9682 × 10-2-1.4
6430590A07Rik'LDB1 knock-down' vs 'control shRNA'RNA interferenceRole of LDB1 in the transition from chromatin looping to transcription activation
Adjusted p-valueLog2-fold change
2.9217 × 10-7-1.3
6430590A07Rik'Trichuris muris' vs 'control' in 'non wormy; caecum'environmental stress, infect, organism partRNA-seq of mouse intestinal mucosa to investigate infection by the parasitic nematode Trichuris muris
Adjusted p-valueLog2-fold change
1.4847 × 10-5-1.3
6430590A07Rik'lipopolysaccharide; 10 nanogram per milliliter and prostaglandin E2; 1 micromolar' vs 'none' in 'primary cell line; wild type genotype'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
1.1122 × 10-2-1.3
6430590A07Rik'wormy, worm left; Trichuris muris' vs 'control; non wormy' in 'caecum'environmental stress, infect, organism partRNA-seq of mouse intestinal mucosa to investigate infection by the parasitic nematode Trichuris muris
Adjusted p-valueLog2-fold change
4.8795 × 10-21.3
6430590A07Rik'induced extraembryonic endoderm stem cell; grown in ES cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
7.9087 × 10-5-1.2
6430590A07Rik'wormy, worm separated; Trichuris muris' vs 'control; non wormy' in 'caecum'environmental stress, infect, organism partRNA-seq of mouse intestinal mucosa to investigate infection by the parasitic nematode Trichuris muris
Adjusted p-valueLog2-fold change
1.2167 × 10-31.2
6430590A07Rik'artesunate and chloroquine (at same dosage); 30 milligram per kilogram' at '10 day' vs 'none' at '7 day' in 'Plasmodium berghei ANKA'compound, infect, sampling time pointRNA-seq analysis of anti-malarial drug chemotherapy of murine experimental Cerebral Malaria (ECM)
Adjusted p-valueLog2-fold change
2.865 × 10-21.2
6430590A07Rik'LDB1 knock-down with Ldb1 delta 4/5 construct' vs 'control shRNA'RNA interferenceRole of LDB1 in the transition from chromatin looping to transcription activation
Adjusted p-valueLog2-fold change
8.3921 × 10-6-1.1
6430590A07Rik'lipopolysaccharide; 10 nanogram per milliliter' vs 'none' in 'primary cell line; wild type genotype'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
1.7155 × 10-2-1.1
6430590A07Rik'synovial sarcoma' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
2.2988 × 10-21.1
6430590A07Rik'actinomycin D; 4 hour' vs 'none' in 'Alb-Cre-ERT2 / Cnot1 flox/flox'compound, genotype, timeRNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice
Adjusted p-valueLog2-fold change
2.2982 × 10-41
6430590A07Rik'rosiglitazone; 100 nanomolar' vs 'none' in 'wild type genotype'compound, genotypeTranscriptional response to Rosiglitazone in adipocyte progenitors isolated from WT and Cited4-KO scWAT
Adjusted p-valueLog2-fold change
2.6667 × 10-3-1
6430590A07Rik'Irx3 knockout' vs 'control' at '7 day'genetic modification, timeRNA-Seq of mouse Irx3-KO and Control ME3 cells on days 1 and 7 of adipogenic differentiation
Adjusted p-valueLog2-fold change
1.2573 × 10-2-1
6430590A07Rik'inducible deletion of Mll' vs 'control'treatmentMLL regulated genes in LSK/CD48- hematopoietic stem cells
Adjusted p-valueLog2-fold change
1.9699 × 10-21
6430590A07Rik'neurosphere in differentiation medium; 1 day' vs 'neurosphere; 0 day' in 'Cstb knockout'genotype, growth condition, timeTranscriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation
Adjusted p-valueLog2-fold change
2.6204 × 10-2-1
6430590A07Rik'Tumor Necrosis Factor' vs 'none'stimulusTranscription profiling by high throughput sequencing of CD8 single positive thymocytes from F5 Rag1KO TCR transgenic mice stimulated with tumor necrosis factor
Synonym
EG619719
Ensembl gene
Ensembl transcript
Entrez
MGI ID (Mouse)
MGI description
Gene biotype
Design element
4430354, ILMN_2584805, 4869380, 166826_at, A_55_P2236823, 1442536_at, 5186644, 17404997, 5016112, A_51_P446112