5.8 | | Gm44253 | 'soticlestat; 30 milligram per kilogram' vs 'none' in 'astrocyte; none' | cell type, compound, disease | RNA-seq profiling of three distinct cell populations in a murine model of epilepsia with and without drug treatment |
-5.4 | | Gm44253 | 'AZD5069; 100 milligram per kilogram' vs 'none' | compound | RNA-seq to investigate differentially expressed genes in KPC mouse PDAC treated with CSF-1R small molecule inhibitor AZD7507 and/or the CXCR2 small molecule inhibitor AZD5069 |
5.4 | | Gm44253 | 'cortical epithelial cell; Lin- Dapi-EpCAM+ CD31-UEA1-Ly51+ td-tomato+t vs 'medullary epithelial cell; Lin- Dapi-EpCAM+ CD31-UEA1+Ly51- td-tomato-' | cell type, phenotype | Thymic T-cell progenitor development is supported by membrane bound Kit ligand provided by a combined vascular endothelial and epithelial niche. |
-5.3 | | Gm44253 | 'status epilepticus' vs 'none' in 'astrocyte; soticlestat; 30 milligram per kilogram' | cell type, compound, disease | RNA-seq profiling of three distinct cell populations in a murine model of epilepsia with and without drug treatment |
-4.4 | | Gm44253 | 'AZD7507; AZD5069 (at same dosage); 100 milligram per kilogram' vs 'none' | compound | RNA-seq to investigate differentially expressed genes in KPC mouse PDAC treated with CSF-1R small molecule inhibitor AZD7507 and/or the CXCR2 small molecule inhibitor AZD5069 |
-4 | | Gm44253 | 'PTEN null' vs 'wild type genotype' | genotype | RNA seq of prostate gland from WT, PTEN pc -/- and PTEN pc-/-;P53 -/- mice |
-3.8 | | Gm44253 | 'PTEN null, P53-/-' vs 'wild type genotype' | genotype | RNA seq of prostate gland from WT, PTEN pc -/- and PTEN pc-/-;P53 -/- mice |
-3 | | Gm44253 | 'extracellular vesicle; EMT cell culture medium' vs 'none' | sampling site, stimulus | Cellular and extracellular vesicle RNA sequence for E-cadherin-RFP EMT reporter system expressing mouse breast cancer cell line Py2T during EMT/MET |
-2.7 | | Gm44253 | 'extracellular vesicle; MET cell culture medium' vs 'none' | sampling site, stimulus | Cellular and extracellular vesicle RNA sequence for E-cadherin-RFP EMT reporter system expressing mouse breast cancer cell line Py2T during EMT/MET |
-1.5 | | Gm44253 | 'PF-04691502–resistant cell; 1 micromolar; PF-04691502 removed for 48 hours' vs 'parental AKP cell; dimethyl sulfoxide' | compound, phenotype | Resistance to PI3K/mTOR inhibitor PF-04691502 in KRAS mutant colorectal cancer models reveals a sensitivity to combination with EGFR inhibition |
1.4 | | Gm44253 | 'doxycycline; 200 nanogram per milliliter; neoplasm; 12 day' vs 'none; normal; 0 day' | compound, phenotype, time | RNA-seq of doxycycline induced tumor and residual mouse primary mammary epithelial cells grown in 3D cell cultures against non-induced controls |