-4.3 | | Gm4356 | 'AZD5069; 100 milligram per kilogram' vs 'none' | compound | RNA-seq to investigate differentially expressed genes in KPC mouse PDAC treated with CSF-1R small molecule inhibitor AZD7507 and/or the CXCR2 small molecule inhibitor AZD5069 |
3.6 | | Gm4356 | 'Vgamma6+, IL-17+' at '21 month' vs '3 month' | age, phenotype | RNA sequencing of gamma-delta T cell subsets from young and old mice |
-3.5 | | Gm4356 | 'AZD7507; AZD5069 (at same dosage); 100 milligram per kilogram' vs 'none' | compound | RNA-seq to investigate differentially expressed genes in KPC mouse PDAC treated with CSF-1R small molecule inhibitor AZD7507 and/or the CXCR2 small molecule inhibitor AZD5069 |
-3.1 | | Gm4356 | 'germ free C57BL/6' vs 'specific pathogen free C57BL/6' in 'wild type genotype' | genotype, strain | RNA sequencing of primary isolated unstimulated murine splenic cDC from specific pathogen free (SPF), Germ Free (GF) and Interferon alpha/beta receptor 1 (Ifnar) knock out mice. |
-3 | | Gm4356 | 'Ifnar1 knockout' vs 'wild type genotype' in 'specific pathogen free C57BL/6' | genotype, strain | RNA sequencing of primary isolated unstimulated murine splenic cDC from specific pathogen free (SPF), Germ Free (GF) and Interferon alpha/beta receptor 1 (Ifnar) knock out mice. |
2.9 | | Gm4356 | 'induced extraembryonic endoderm stem cell; grown in ES cell medium' vs 'mouse embryonic fibroblast; control' | cell type, growth condition | OSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells |
2.8 | | Gm4356 | 'reduced expression of miR-25' vs 'wild type' | phenotype | Transcription profiling by high throughput sequencing of wild type and miR-25 agomir or antagomir treated mice |
-2.7 | | Gm4356 | 'PTEN null' vs 'wild type genotype' | genotype | RNA seq of prostate gland from WT, PTEN pc -/- and PTEN pc-/-;P53 -/- mice |
2.6 | | Gm4356 | 'MEF2A knockout' vs 'wild type genotype' in 'Hoxb8-FL; lipopolysaccharide; 10 nanogram per milliliter' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
-2.2 | | Gm4356 | 'Salmonella enterica serovar Typhimurium' vs 'control' in 'bone marrow macrophage from 129P2 mouse strain' | clinical information, infect | Gene expression profiles of mouse embryonic stem cell derived macrophages infected with Salmonella typhimurium |
-2 | | Gm4356 | 'undifferentiated' vs 'differentiated; rosiglitazone' in 'F1.129xB6' | phenotype, stimulus, strain | RNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail |
-1.9 | | Gm4356 | 'ABIN1[D485N] knock-in' vs 'wild type genotype' in 'neutrophil' | cell type, genotype | RNA-seq of inflammatory monocytes, patrolling monocytes and neutrophils in wild type and ABIN1[D485N] mice |
-1.9 | | Gm4356 | 'Alb-Cre-ERT2 / Cnot1 flox/flox' vs 'Cnot1 flox/flox' in 'none' | compound, genotype, time | RNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice |
-1.8 | | Gm4356 | 'lipopolysaccharide; 10 nanogram per milliliter' vs 'none' in 'primary cell line; wild type genotype' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
-1.4 | | Gm4356 | 'brown adipose tissue' vs 'white adipose tissue' in 'chow; 23 degree celsius' | diet, organism part, temperature | RNA-seq of brown and white mouse adipose tissue at thermoneutrality and high-fat diet |
1 | | Gm4356 | 'interferon gamma; 10 nanogram per milliliter and interleukin-13; 10 nanogram per milliliter' vs 'none' | compound | RNAseq of small intestinal organoids from mice treated with the cytokines IFNG, IL-13 and IL-22 for 24 hours |
-1 | | Gm4356 | 'α-GalCer; 2 microgram' vs 'none' in 'Cd1d homozyous knockout' | compound, genotype | CD1d-dependent immune suppression mediated by regulatory B cells through modulations of iNKT cells |