ENSRNOG00000002607 (Sox9)

rattus norvegicus

SRY-box transcription factor 9

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Rattus norvegicus
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Showing 1 experiment:
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Display log2-fold change
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Log2-fold changeSpeciesGene nameComparisonExperimental variablesExperiment name
Adjusted p-valueLog2-fold change
6.274 × 10-62.9
Sox9'methapyrilene; 100 milligram per kilogram' vs 'none' in 'methapyrilene; liver' at '29 day'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from repeat dosing studies: compounds starting with J to M.
Adjusted p-valueLog2-fold change
2.128 × 10-7-2.7
Sox9'female kidney' vs 'male kidney'organism part, sexIdentification of sexually dimorphically expressed genes in rat tissues
Adjusted p-valueLog2-fold change
7.3338 × 10-72.7
Sox9'caffeine; 100 milligram per kilogram' vs 'none' in 'caffeine; liver' at '24 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
1.7507 × 10-11-2.5
Sox9'allopurinol; 50 milligram per kilogram' vs 'none' in 'allopurinol; liver' at '24 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with A.
Adjusted p-valueLog2-fold change
2.9202 × 10-19-2.4
Sox9'allopurinol; 15 milligram per kilogram' vs 'none' in 'allopurinol; liver' at '24 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with A.
Adjusted p-valueLog2-fold change
2.6321 × 10-13-2.4
Sox9'acetazolamide; 60 milligram per kilogram' vs 'none' in 'acetazolamide; kidney' at '6 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with A.
Adjusted p-valueLog2-fold change
3.4542 × 10-82.4
Sox9'acetazolamide; 60 milligram per kilogram' vs 'none' in 'acetazolamide; liver' at '9 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with A.
Adjusted p-valueLog2-fold change
2.8058 × 10-182.3
Sox9'allopurinol; 15 milligram per kilogram' vs 'none' in 'allopurinol; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with A.
Adjusted p-valueLog2-fold change
1.4581 × 10-152.3
Sox9'acetazolamide; 60 milligram per kilogram' vs 'none' in 'acetazolamide; liver' at '24 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with A.
Adjusted p-valueLog2-fold change
5.8698 × 10-15-2.3
Sox9'erythromycin ethylsuccinate; 1000 milligram per kilogram' vs 'none' in 'erythromycin ethylsuccinate; kidney' at '24 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with D and E.
Adjusted p-valueLog2-fold change
1.1377 × 10-132.3
Sox9'nitrofurantoin; 10 milligram per kilogram' vs 'none' in 'nitrofurantoin; liver' at '6 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with N to O.
Adjusted p-valueLog2-fold change
1.6189 × 10-112.3
Sox9'caffeine; 10 milligram per kilogram' vs 'none' in 'caffeine; liver' at '9 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
3.3145 × 10-9-2.3
Sox9'omeprazole; 100 milligram per kilogram' vs 'none' in 'omeprazole; kidney' at '9 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with N to O.
Adjusted p-valueLog2-fold change
8.1845 × 10-72.3
Sox9'carboplatin; 30 milligram per kilogram' vs 'none' in 'carboplatin; liver' at '6 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
1.0709 × 10-102.2
Sox9'cyclosporine A; 300 milligram per kilogram' vs 'none' in 'cyclosporine A; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
1.9139 × 10-102.2
Sox9'cephalothin; 300 milligram per kilogram' vs 'none' in 'cephalothin; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
5.2259 × 10-102.2
Sox9'caffeine; 10 milligram per kilogram' vs 'none' in 'caffeine; liver' at '24 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
9.7286 × 10-14-2.1
Sox9'omeprazole; 1000 milligram per kilogram' vs 'none' in 'omeprazole; kidney' at '9 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with N to O.
Adjusted p-valueLog2-fold change
6.8116 × 10-11-2.1
Sox9'erythromycin ethylsuccinate; 100 milligram per kilogram' vs 'none' in 'erythromycin ethylsuccinate; liver' at '9 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with D and E.
Adjusted p-valueLog2-fold change
2.0955 × 10-13-2
Sox9'nitrofurantoin; 600 milligram per kilogram' vs 'none' in 'nitrofurantoin; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with N to O.
Adjusted p-valueLog2-fold change
1.1456 × 10-122
Sox9'captopril; 100 milligram per kilogram' vs 'none' in 'captopril; liver' at '9 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
2.3946 × 10-72
Sox9'bromoethylamine; 6 milligram per kilogram' vs 'none' in 'bromoethylamine; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with B.
Adjusted p-valueLog2-fold change
6.4492 × 10-131.9
Sox9'captopril; 300 milligram per kilogram' vs 'none' in 'captopril; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
1.4715 × 10-111.9
Sox9'omeprazole; 100 milligram per kilogram' vs 'none' in 'omeprazole; liver' at '6 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with N to O.
Adjusted p-valueLog2-fold change
1.3693 × 10-10-1.9
Sox9'ethionine; 80 milligram per kilogram' vs 'none' in 'ethionine; liver' at '24 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with D and E.
Adjusted p-valueLog2-fold change
1.3819 × 10-10-1.9
Sox9'imipramine; 30 milligram per kilogram' vs 'none' in 'imipramine; liver' at '6 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with F to I.
Adjusted p-valueLog2-fold change
3.2779 × 10-91.9
Sox9'imipramine; 30 milligram per kilogram' vs 'none' in 'imipramine; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with F to I.
Adjusted p-valueLog2-fold change
3.5493 × 10-91.9
Sox9'cisplatin; 3 milligram per kilogram' vs 'none' in 'cisplatin; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
3.8975 × 10-91.9
Sox9'gentamicin; 10 milligram per kilogram' vs 'none' in 'gentamicin; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with F to I.
Adjusted p-valueLog2-fold change
2.1269 × 10-51.9
Sox9'bromoethylamine; 60 milligram per kilogram' vs 'none' in 'bromoethylamine; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with B.
Adjusted p-valueLog2-fold change
2.3092 × 10-131.8
Sox9'cyclophosphamide; 5 milligram per kilogram' vs 'none' in 'cyclophosphamide; liver' at '6 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
2.4738 × 10-10-1.8
Sox9'puromycin aminonucleoside; 120 milligram per kilogram' vs 'none' in 'puromycin aminonucleoside; liver' at '6 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with P to R.
Adjusted p-valueLog2-fold change
6.1993 × 10-91.8
Sox9'puromycin aminonucleoside; 120 milligram per kilogram' vs 'none' in 'puromycin aminonucleoside; liver' at '24 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with P to R.
Adjusted p-valueLog2-fold change
7.1233 × 10-9-1.8
Sox9'cyclophosphamide; 150 milligram per kilogram' vs 'none' in 'cyclophosphamide; liver' at '24 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
1.9307 × 10-7-1.8
Sox9'imipramine; 100 milligram per kilogram' vs 'none' in 'imipramine; liver' at '6 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with F to I.
Adjusted p-valueLog2-fold change
5.4542 × 10-5-1.8
Sox9'ethinylestradiol; 1 milligram per kilogram' vs 'none' in 'ethinylestradiol; kidney' at '29 day'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from repeat dosing studies: compounds starting with D to E.
Adjusted p-valueLog2-fold change
2.457 × 10-4-1.8
Sox9'ethinylestradiol; 3 milligram per kilogram' vs 'none' in 'ethinylestradiol; kidney' at '29 day'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from repeat dosing studies: compounds starting with D to E.
Adjusted p-valueLog2-fold change
3.2958 × 10-81.7
Sox9'nitrofurantoin; 10 milligram per kilogram' vs 'none' in 'nitrofurantoin; liver' at '9 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with N to O.
Adjusted p-valueLog2-fold change
3.6913 × 10-61.7
Sox9'bromobenzene; 30 milligram per kilogram' vs 'none' in 'bromobenzene; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with B.
Adjusted p-valueLog2-fold change
3.7508 × 10-61.7
Sox9'adenovirus-mediated Nkx6.1' vs 'none'phenotypeNkx6.1 regulates islet beta-cell proliferation via Nr4a1 and Nr4a3 nuclear receptors
Adjusted p-valueLog2-fold change
2.0817 × 10-4-1.7
Sox9'ethinylestradiol; 10 milligram per kilogram' vs 'none' in 'ethinylestradiol; kidney' at '8 day'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from repeat dosing studies: compounds starting with D to E.
Adjusted p-valueLog2-fold change
3.705 × 10-3-1.6
Sox9'bromobenzene; 100 milligram per kilogram' vs 'none' in 'bromobenzene; liver' at '6 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with B.
Adjusted p-valueLog2-fold change
1.1388 × 10-10-1.5
Sox9'cyclophosphamide; 50 milligram per kilogram' vs 'none' in 'cyclophosphamide; liver' at '9 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
3.7475 × 10-7-1.5
Sox9'collagen sandwich' at '8 day' vs 'monolayer culture' at '8 day'growth condition, timeGenome-wide gene expression profiles of primary hepatocytes in two different culture systems over an 8-day period
Adjusted p-valueLog2-fold change
6.0167 × 10-6-1.5
Sox9'bromoethylamine; 20 milligram per kilogram' vs 'none' in 'bromoethylamine; liver' at '24 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with B.
Adjusted p-valueLog2-fold change
1.1158 × 10-4-1.5
Sox9'indomethacin; 15 milligram per kilogram' vs 'none' in 'indomethacin; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with F to I.
Adjusted p-valueLog2-fold change
2.5897 × 10-41.5
Sox9'epididymal fat' vs 'retroperitoneal fat'organism partTranscription profiling of rat epididymal and retroperitoneal fat
Adjusted p-valueLog2-fold change
3.8743 × 10-4-1.5
Sox9'ethinylestradiol; 10 milligram per kilogram' vs 'none' in 'ethinylestradiol; kidney' at '29 day'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from repeat dosing studies: compounds starting with D to E.
Adjusted p-valueLog2-fold change
2.059 × 10-3-1.5
Sox9'cobalt chloride; 310 micromolar' vs 'none' in 'MH1C1'cell line, compoundExposure to Cobalt Causes Transcriptomic and Proteomic Changes in Two Rat Liver Derived Cell Lines
Adjusted p-valueLog2-fold change
1.084 × 10-9-1.4
Sox9'ketoconazole; 10 milligram per kilogram' vs 'none' in 'ketoconazole; liver' at '6 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with J to M.
Adjusted p-valueLog2-fold change
1.9658 × 10-8-1.4
Sox9'cyclophosphamide; 150 milligram per kilogram' vs 'none' in 'cyclophosphamide; liver' at '9 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
1.6946 × 10-41.4
Sox9'transforming growth factor beta 1' vs 'none'stimulusWhole transcriptome analysis of rat peritoneal cells in a TGFβ1 induced mesothelial-to-mesenchymal transition
Adjusted p-valueLog2-fold change
2.8554 × 10-4-1.4
Sox9'ethinylestradiol; 3 milligram per kilogram' vs 'none' in 'ethinylestradiol; kidney' at '15 day'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from repeat dosing studies: compounds starting with D to E.
Adjusted p-valueLog2-fold change
6.6532 × 10-4-1.4
Sox9'ethinylestradiol; 3 milligram per kilogram' vs 'none' in 'ethinylestradiol; kidney' at '8 day'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from repeat dosing studies: compounds starting with D to E.
Adjusted p-valueLog2-fold change
2.1545 × 10-3-1.4
Sox9'ethinylestradiol; 10 milligram per kilogram' vs 'none' in 'ethinylestradiol; kidney' at '15 day'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from repeat dosing studies: compounds starting with D to E.
Adjusted p-valueLog2-fold change
1.6242 × 10-21.4
Sox9'17beta-estradiol; 10 microgram per kilogram per day; male' vs '17beta-estradiol; 0 microgram per kilogram per day; male'compound, sexTranscription profiling by array of rat male and female mammary glands following exposure to exogenous estradiol
Adjusted p-valueLog2-fold change
2.8068 × 10-20-1.3
Sox9'chlorpyrifos (50 nanomolar) and ethylenethiourea (0.6 nanomolar)' vs 'none'compoundRNA-seq of immortalized rat thyrocytes (PCCl3) treated with two thyroid disrupting chemicals (ethylenethiourea and chlorpyrifos) against untreated controls
Adjusted p-valueLog2-fold change
1.4094 × 10-5-1.3
Sox9'indomethacin; 50 milligram per kilogram' vs 'none' in 'indomethacin; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with F to I.
Adjusted p-valueLog2-fold change
6.0708 × 10-4-1.3
Sox9'allyl alcohol; 10 milligram per kilogram' vs 'none' in 'allyl alcohol; liver' at '9 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with A.
Adjusted p-valueLog2-fold change
7.4252 × 10-41.3
Sox9'neuromuscular junction' vs 'non-neuromuscular junction' in 'tibialis anterior'organism part, sampling siteTranscription profiling by array of fiber and neuromuscular junctions in Rattus norvegicus extraocular and tibialis anterior muscles
Adjusted p-valueLog2-fold change
1.1071 × 10-21.3
Sox9'puromycin aminonucleoside; 12 milligram per kilogram' vs 'none' in 'puromycin aminonucleoside; liver' at '9 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with P to R.
Adjusted p-valueLog2-fold change
1.6684 × 10-2-1.3
Sox9'phenylbutazone; 200 milligram per kilogram' vs 'none' in 'phenylbutazone; liver' at '6 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with P to R.
Adjusted p-valueLog2-fold change
4.1387 × 10-2-1.3
Sox9'thioacetamide; 15 milligram per kilogram' vs 'none' in 'thioacetamide; liver' at '6 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with S to T.
Adjusted p-valueLog2-fold change
4.7246 × 10-21.3
Sox9'enalapril; 200 milligram per kilogram' vs 'none' in 'enalapril; liver' at '24 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with D and E.
Adjusted p-valueLog2-fold change
1.9406 × 10-61.2
Sox9'acetazolamide; 600 milligram per kilogram' vs 'none' in 'acetazolamide; liver' at '24 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with A.
Adjusted p-valueLog2-fold change
2.3147 × 10-41.2
Sox9'methapyrilene; 100 milligram per kilogram' vs 'none' in 'methapyrilene; liver' at '15 day'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from repeat dosing studies: compounds starting with J to M.
Adjusted p-valueLog2-fold change
1.223 × 10-3-1.2
Sox9'ethinylestradiol; 1 milligram per kilogram' vs 'none' in 'ethinylestradiol; kidney' at '15 day'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from repeat dosing studies: compounds starting with D to E.
Adjusted p-valueLog2-fold change
6.0003 × 10-31.2
Sox9'phenylbutazone; 20 milligram per kilogram' vs 'none' in 'phenylbutazone; liver' at '9 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with P to R.
Adjusted p-valueLog2-fold change
1.0136 × 10-21.2
Sox9'squamous cell carcinoma' vs 'normal' in 'epithelial cell'cell type, diseaseTranscription profiling by array of rat tongue epithelia and submucosal fibroblasts during oral carcinogenesis
Adjusted p-valueLog2-fold change
1.1433 × 10-21.2
Sox9'bromobenzene; 100 milligram per kilogram' vs 'none' in 'bromobenzene; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with B.
Adjusted p-valueLog2-fold change
1.2095 × 10-21.2
Sox9'rifampicin; 60 milligram per kilogram' vs 'none' in 'rifampicin; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with P to R.
Adjusted p-valueLog2-fold change
2.0014 × 10-21.2
Sox9'thioacetamide; 15 milligram per kilogram' vs 'none' in 'thioacetamide; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with S to T.
Adjusted p-valueLog2-fold change
2.7856 × 10-21.2
Sox9'nitrofurantoin; 100 milligram per kilogram' vs 'none' in 'nitrofurantoin; liver' at '9 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with N to O.
Adjusted p-valueLog2-fold change
4.6943 × 10-21.2
Sox9'acetamidofluorene; 30 milligram per kilogram' vs 'none' in 'acetamidofluorene; liver' at '29 day'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from repeat dosing studies: compounds starting with A.
Adjusted p-valueLog2-fold change
3.5794 × 10-15-1.1
Sox9'chlorpyrifos (5 naomolar) and ethylenethiourea (6 nanomolar)' vs 'none'compoundRNA-seq of immortalized rat thyrocytes (PCCl3) treated with two thyroid disrupting chemicals (ethylenethiourea and chlorpyrifos) against untreated controls
Adjusted p-valueLog2-fold change
1.7118 × 10-71.1
Sox9'2 weeks after L5 spinal nerve ligation' vs 'control'growth condition, timeRNA-seq of rat dorsal root ganglia after ligation to investigate central nervous system transcriptomics in chronic pain using agnostic splice site discovery methods
Adjusted p-valueLog2-fold change
1.1115 × 10-61.1
Sox9'allyl alcohol; 10 milligram per kilogram' vs 'none' in 'allyl alcohol; liver' at '6 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with A.
Adjusted p-valueLog2-fold change
4.9274 × 10-6-1.1
Sox9'ciprofloxacin; 300 milligram per kilogram' vs 'none' in 'ciprofloxacin; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
2.0482 × 10-2-1.1
Sox9'cyclosporine A; 100 milligram per kilogram' vs 'none' in 'cyclosporine A; liver' at '6 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
2.2742 × 10-2-1.1
Sox9'clofibrate; 30 milligram per kilogram' vs 'none' in 'clofibrate; liver' at '6 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
4.0369 × 10-21.1
Sox9'17beta-estradiol; 1 microgram per kilogram per day; male' vs '17beta-estradiol; 0 microgram per kilogram per day; male'compound, sexTranscription profiling by array of rat male and female mammary glands following exposure to exogenous estradiol
Adjusted p-valueLog2-fold change
7.4482 × 10-14-1
Sox9'chlorpyrifos (5 nanomolar) and ethylenethiourea (60 nanomolar)' vs 'none'compoundRNA-seq of immortalized rat thyrocytes (PCCl3) treated with two thyroid disrupting chemicals (ethylenethiourea and chlorpyrifos) against untreated controls
Adjusted p-valueLog2-fold change
7.4367 × 10-41
Sox9'naphthyl isothiocyanate; 15 milligram per kilogram' vs 'none' in 'naphthyl isothiocyanate; liver' at '29 day'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from repeat dosing studies: compounds starting with N to O.
Adjusted p-valueLog2-fold change
1.1324 × 10-3-1
Sox9'puromycin aminonucleoside; 12 milligram per kilogram' vs 'none' in 'puromycin aminonucleoside; kidney' at '29 day'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from repeat dosing studies: compounds starting with P to R.
Adjusted p-valueLog2-fold change
4.3474 × 10-31
Sox9'dysplasia' vs 'normal' in 'epithelial cell'cell type, diseaseTranscription profiling by array of rat tongue epithelia and submucosal fibroblasts during oral carcinogenesis
Adjusted p-valueLog2-fold change
9.1316 × 10-31
Sox9'24 hour culture at sarcomere length = 1.8 microns' vs 'control'stimulusRNA-Seq of rat myocardial slices cultured with biomimetic electromechanical stimulation
Adjusted p-valueLog2-fold change
1.0399 × 10-21
Sox9'bucetin; 300 milligram per kilogram' vs 'none' in 'bucetin; liver' at '9 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with B.
Adjusted p-valueLog2-fold change
1.2986 × 10-2-1
Sox9'5 day' vs '0 day'timeTranscription profiling of rat trinitrobencenesulfonic acid (TNBS)-induced colitis model 2, 5, 7 and 14 days after TNBS treatment
Adjusted p-valueLog2-fold change
1.2986 × 10-2-1
Sox9'experimental colitis' at '5 day' vs 'normal'disease, timeTranscription profiling of rats with colitis induced with trinitrobenzene sulfonate - time series
Adjusted p-valueLog2-fold change
1.6701 × 10-2-1
Sox9'bucetin; 300 milligram per kilogram' vs 'none' in 'bucetin; liver' at '24 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with B.
Adjusted p-valueLog2-fold change
2.1583 × 10-21
Sox9'phenylbutazone; 200 milligram per kilogram' vs 'none' in 'phenylbutazone; liver' at '9 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with P to R.
Adjusted p-valueLog2-fold change
2.9378 × 10-2-1
Sox9'phenylbutazone; 60 milligram per kilogram' vs 'none' in 'phenylbutazone; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with P to R.