ENSRNOG00000005807 (Ptpn7)

rattus norvegicus

protein tyrosine phosphatase, non-receptor type 7

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Rattus norvegicus
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Showing 12 experiments:
Created with Highcharts 6.2.0adrenal glandbraincalcaneal tendoncolonforepaw flexor tendongastrocnemiusheartkidneyliverlungpatellar tendonskeletal muscle tissuespleensupraspinatus tendontestisthymusuterus
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11 Yu - male, juvenile
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11 Yu - male, elderly
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11 Yu - male, adult
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11 Yu - male, adolescent
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11 Yu - female, juvenile
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11 Yu - female, elderly
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11 Yu - female, adult
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11 Yu - female, adolescent
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9 Merkin - Sprague-Dawley
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9 Merkin - F344/Cr1
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9 Merkin - BN/SsNHsd
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Organism parts - tendons - Mendias et al
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Proteomics
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Transcriptomics
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-1.4
-1.7
1.1
2.2
Display log2-fold change
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Log2-fold changeSpeciesGene nameComparisonExperimental variablesExperiment name
Adjusted p-valueLog2-fold change
2.0085 × 10-42.2
Ptpn7'acquired epilepsy (VX-765)' vs 'normal'compound, diseaseTranscriptional profiling of rats with acquired epilepsy treated with two antiinflammatory drugs, VX-765 or Anakinra to study the blockade of IL-1β-mediated signaling in status epilepticus
Adjusted p-valueLog2-fold change
1.8475 × 10-41.9
Ptpn7'acquired epilepsy (anakinra and VX-765)' vs 'normal'compound, diseaseTranscriptional profiling of rats with acquired epilepsy treated with two antiinflammatory drugs, VX-765 or Anakinra to study the blockade of IL-1β-mediated signaling in status epilepticus
Adjusted p-valueLog2-fold change
1.4621 × 10-10-1.7
Ptpn7'24 hour culture at sarcomere length = 2.2 microns' vs 'control'stimulusRNA-Seq of rat myocardial slices cultured with biomimetic electromechanical stimulation
Adjusted p-valueLog2-fold change
1.2133 × 10-6-1.4
Ptpn7'arteriotomy' at '48 hour' vs 'control' at '48 hour'injury, timeTranscription profiling of rat carotid artery following arteriotomy
Adjusted p-valueLog2-fold change
4.0214 × 10-6-1.4
Ptpn7'24 hour culture at sarcomere length = 1.8 microns' vs 'control'stimulusRNA-Seq of rat myocardial slices cultured with biomimetic electromechanical stimulation
Adjusted p-valueLog2-fold change
7.1975 × 10-51.2
Ptpn7'nitrosodiethylamine; 30 milligram per kilogram' vs 'none' in 'nitrosodiethylamine; liver' at '8 day'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from repeat dosing studies: compounds starting with N to O.
Adjusted p-valueLog2-fold change
1.1827 × 10-91.1
Ptpn7'ketoconazole; 10 milligram per kilogram' vs 'none' in 'ketoconazole; liver' at '6 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with J to M.
Adjusted p-valueLog2-fold change
2.8458 × 10-61.1
Ptpn7'ciprofloxacin; 300 milligram per kilogram' vs 'none' in 'ciprofloxacin; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
1.1081 × 10-41.1
Ptpn7'thioacetamide; 45 milligram per kilogram' vs 'none' in 'thioacetamide; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with S to T.
Adjusted p-valueLog2-fold change
1.373 × 10-31.1
Ptpn7'allopurinol; 150 milligram per kilogram' vs 'none' in 'allopurinol; kidney' at '29 day'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from repeat dosing studies: compounds starting with A.