ENSRNOG00000012046 (Prmt5)

rattus norvegicus

protein arginine methyltransferase 5

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Rattus norvegicus
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Showing 12 experiments:
Created with Highcharts 6.2.0adrenal glandbraincalcaneal tendoncolonforepaw flexor tendongastrocnemiusheartkidneyliverlungpatellar tendonskeletal muscle tissuespleensupraspinatus tendontestisthymusuterus
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11 Yu - male, juvenile
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11 Yu - male, elderly
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11 Yu - male, adult
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11 Yu - male, adolescent
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11 Yu - female, juvenile
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11 Yu - female, elderly
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11 Yu - female, adult
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11 Yu - female, adolescent
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9 Merkin - Sprague-Dawley
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9 Merkin - F344/Cr1
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9 Merkin - BN/SsNHsd
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Organism parts - tendons - Mendias et al
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Proteomics
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Transcriptomics
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Display log2-fold change
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Log2-fold changeSpeciesGene nameComparisonExperimental variablesExperiment name
Adjusted p-valueLog2-fold change
3.8571 × 10-51.4
Prmt5'thioacetamide; 45 milligram per kilogram' vs 'none' in 'thioacetamide; liver' at '15 day'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from repeat dosing studies: compounds starting with S to T.
Adjusted p-valueLog2-fold change
1.0438 × 10-41.4
Prmt5'thioacetamide; 45 milligram per kilogram' vs 'none' in 'thioacetamide; liver' at '29 day'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from repeat dosing studies: compounds starting with S to T.
Adjusted p-valueLog2-fold change
5.8952 × 10-8-1.3
Prmt5'ciprofloxacin; 300 milligram per kilogram' vs 'none' in 'ciprofloxacin; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
7.8893 × 10-61.3
Prmt5'ethambutol; 1000 milligram per kilogram' vs 'none' in 'ethambutol; liver' at '8 day'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from repeat dosing studies: compounds starting with D to E.
Adjusted p-valueLog2-fold change
1.1643 × 10-2-1.3
Prmt5'bisphenol A; 10^-9 molar' at '7 day' vs 'control; 10^-9 molar' at '7 day'compound, timeAssessment of low-dose bisphenol A (BPA) toxicity in rat thyroid follicular cells by gene expression microarray
Adjusted p-valueLog2-fold change
6.8928 × 10-9-1.2
Prmt5'ketoconazole; 10 milligram per kilogram' vs 'none' in 'ketoconazole; liver' at '6 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with J to M.
Adjusted p-valueLog2-fold change
2.7781 × 10-51.2
Prmt5'methapyrilene; 100 milligram per kilogram' vs 'none' in 'methapyrilene; liver' at '15 day'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from repeat dosing studies: compounds starting with J to M.
Adjusted p-valueLog2-fold change
3.4785 × 10-181.1
Prmt5'24 hour culture at sarcomere length = 2.2 microns' vs 'control'stimulusRNA-Seq of rat myocardial slices cultured with biomimetic electromechanical stimulation
Adjusted p-valueLog2-fold change
3.1041 × 10-151.1
Prmt5'24 hour culture at sarcomere length = 1.8 microns' vs 'control'stimulusRNA-Seq of rat myocardial slices cultured with biomimetic electromechanical stimulation
Adjusted p-valueLog2-fold change
9.5529 × 10-51.1
Prmt5'thioacetamide; 45 milligram per kilogram' vs 'none' in 'thioacetamide; liver' at '8 day'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from repeat dosing studies: compounds starting with S to T.
Adjusted p-valueLog2-fold change
1.7144 × 10-31.1
Prmt5'acetamidofluorene; 100 milligram per kilogram' vs 'none' in 'acetamidofluorene; liver' at '29 day'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from repeat dosing studies: compounds starting with A.
Adjusted p-valueLog2-fold change
7.4939 × 10-31.1
Prmt5'acetamidofluorene; 100 milligram per kilogram' vs 'none' in 'acetamidofluorene; liver' at '15 day'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from repeat dosing studies: compounds starting with A.
Adjusted p-valueLog2-fold change
8.4765 × 10-81
Prmt5'cisplatin; 3 milligram per kilogram' vs 'none' in 'cisplatin; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
9.8872 × 10-51
Prmt5'ethambutol; 1000 milligram per kilogram' vs 'none' in 'ethambutol; liver' at '15 day'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from repeat dosing studies: compounds starting with D to E.
Adjusted p-valueLog2-fold change
3.3658 × 10-41
Prmt5'thioacetamide; 45 milligram per kilogram' vs 'none' in 'thioacetamide; liver' at '4 day'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from repeat dosing studies: compounds starting with S to T.
Adjusted p-valueLog2-fold change
1.0115 × 10-31
Prmt5'colchicine; 15 milligram per kilogram' vs 'none' in 'colchicine; liver' at '9 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
1.3821 × 10-31
Prmt5'acetamidofluorene; 30 milligram per kilogram' vs 'none' in 'acetamidofluorene; liver' at '15 day'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from repeat dosing studies: compounds starting with A.
Adjusted p-valueLog2-fold change
3.3423 × 10-31
Prmt5'acetamidofluorene; 30 milligram per kilogram' vs 'none' in 'acetamidofluorene; liver' at '29 day'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from repeat dosing studies: compounds starting with A.
Adjusted p-valueLog2-fold change
1.3886 × 10-21
Prmt5'squamous cell carcinoma' vs 'normal' in 'fibroblast'cell type, diseaseTranscription profiling by array of rat tongue epithelia and submucosal fibroblasts during oral carcinogenesis