ENSRNOG00000013521 (Dhfr)

rattus norvegicus

dihydrofolate reductase

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Rattus norvegicus
Organism part
Showing 12 experiments:
Created with Highcharts 6.2.0adrenal glandbraincalcaneal tendoncolonforepaw flexor tendongastrocnemiusheartkidneyliverlungpatellar tendonskeletal muscle tissuespleensupraspinatus tendontestisthymusuterus
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11 Yu - male, juvenile
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11 Yu - female, juvenile
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11 Yu - male, elderly
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11 Yu - male, adult
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11 Yu - male, adolescent
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11 Yu - female, adolescent
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11 Yu - female, elderly
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11 Yu - female, adult
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9 Merkin - Sprague-Dawley
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9 Merkin - F344/Cr1
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Organism parts - tendons - Mendias et al
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9 Merkin - BN/SsNHsd
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Proteomics
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Transcriptomics
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Experimental variables
Regulation
-1.4
-1.4
1.1
2
Display log2-fold change
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Log2-fold changeSpeciesGene nameComparisonExperimental variablesExperiment name
Adjusted p-valueLog2-fold change
2.9337 × 10-2432
Dhfr'2 weeks after L5 spinal nerve ligation' vs 'control'growth condition, timeRNA-seq of rat dorsal root ganglia after ligation to investigate central nervous system transcriptomics in chronic pain using agnostic splice site discovery methods
Adjusted p-valueLog2-fold change
3.2707 × 10-31.9
Dhfr'sciatic nerve transection for neuropathic pain' vs 'sham surgery'treatmentTranscription profiling of dorsal root ganglia from rats with and without traumatic neuropathic pain from sciatic nerve transection to identify genes responsible for mechanical hypersensitivity
Adjusted p-valueLog2-fold change
3.1648 × 10-2-1.4
Dhfr'5-alpha-dehydrotestestrone' vs 'control'compoundGene expression in rat ovaries treated with DHT
Adjusted p-valueLog2-fold change
1.4527 × 10-21.2
Dhfr'puromycin aminonucleoside; 12 milligram per kilogram' vs 'none' in 'puromycin aminonucleoside; liver' at '15 day'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from repeat dosing studies: compounds starting with P to R.
Adjusted p-valueLog2-fold change
2.1646 × 10-61.1
Dhfr'collagen sandwich' at '8 day' vs 'monolayer culture' at '8 day'growth condition, timeGenome-wide gene expression profiles of primary hepatocytes in two different culture systems over an 8-day period
Synonym
Dhfr1
Ortholog
DHFR (Chlorocebus sabaeus), dhfr-1 (Caenorhabditis elegans), dhfr (Xenopus tropicalis), DHFR (Gallus gallus), DHFR (Bos taurus), ENSTNIG00000004549 (Bos taurus), ENSPANG00000035265 (Canis familiaris), ENSMMUG00000018283 (Macaca mulatta), ENSOCUG00000005127 (Oryctolagus cuniculus), ENSSSCG00000031117 (Sus scrofa), ENSOARG00020016220 (Ciona intestinalis), ENSMMUG00000057255 (Macaca mulatta), ENSECAG00000026827 (Equus caballus), ENSACAG00000010508 (Anolis carolinensis), zgc:153031 (Danio rerio), ENSDNOG00000038425 (Dasypus novemcinctus), DHFR (Pongo abelii), zgc:153031 (Tetraodon nigroviridis), ENSMODG00000044210 (Monodelphis domestica), ENSOARG00020000481 (Pan troglodytes), ENSPANG00000033512 (Salmo salar), DHFR2 (Pongo abelii), ENSMODG00000024860 (Monodelphis domestica), dhfr (Xenopus tropicalis), DHFR (Pan troglodytes), ENSPANG00000033252 (Salmo salar), DHFR2 (Pan troglodytes), ENSMMUG00000004229 (Macaca mulatta), ENSPANG00000035078 (Salmo salar), ENSPANG00000007428 (Papio anubis), ENSCING00000019832 (Ciona intestinalis), DFR1 (Saccharomyces cerevisiae), DHFR2 (Homo sapiens), ENSAPLG00000007336 (Anas platyrhynchos), ENSPANG00000017352 (Papio anubis), DHFR (Homo sapiens), ENSCING00000022228 (Ciona intestinalis), ENSPANG00000023705 (Papio anubis), dhfr (Danio rerio), Dhfr (Mus musculus), Dhfr (Drosophila melanogaster), DHFR (Gorilla gorilla), ENSPANG00000034754 (Ciona intestinalis), ENSOANG00000001607 (Ornithorhynchus anatinus)
Gene ontology
InterPro
Ensembl gene
Ensembl transcript
Ensembl protein
Entrez
UniProt
Gene biotype
Design element
1380669_at, 5625454, 1391660_at, 6480082, 5685595, 6682360, A_44_P837519, A_43_P13103, 6404117, 5708151, 6566110, A_44_P247727, 10812456, rc_AI232898_at, 6209267, 6226399, 5724253, 6021507, 6586865, 6231491, 1370075_at, 6625579, 6045261, rc_AA900413_at, 1383536_at
Reactome pathway ID