ENSRNOG00000018143 (Hpdl)

rattus norvegicus

4-hydroxyphenylpyruvate dioxygenase-like

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Rattus norvegicus
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Showing 6 experiments:
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Log2-fold changeSpeciesGene nameComparisonExperimental variablesExperiment name
Adjusted p-valueLog2-fold change
1.8205 × 10-13-1.6
Hpdl'24 hour culture at sarcomere length = 1.8 microns' vs 'control'stimulusRNA-Seq of rat myocardial slices cultured with biomimetic electromechanical stimulation
Adjusted p-valueLog2-fold change
1.8187 × 10-51.6
Hpdl'adenovirus-mediated Nkx6.1' vs 'none'phenotypeNkx6.1 regulates islet beta-cell proliferation via Nr4a1 and Nr4a3 nuclear receptors
Adjusted p-valueLog2-fold change
7.1208 × 10-13-1.5
Hpdl'24 hour culture at sarcomere length = 2.2 microns' vs 'control'stimulusRNA-Seq of rat myocardial slices cultured with biomimetic electromechanical stimulation
Adjusted p-valueLog2-fold change
2.1247 × 10-6-1.4
Hpdl'erythromycin ethylsuccinate; 1000 milligram per kilogram' vs 'none' in 'erythromycin ethylsuccinate; kidney' at '24 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with D and E.
Adjusted p-valueLog2-fold change
1.0071 × 10-6-1.3
Hpdl'acetazolamide; 60 milligram per kilogram' vs 'none' in 'acetazolamide; kidney' at '6 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with A.
Adjusted p-valueLog2-fold change
1.5252 × 10-51.3
Hpdl'caffeine; 10 milligram per kilogram' vs 'none' in 'caffeine; liver' at '9 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
3.8536 × 10-41.2
Hpdl'acetazolamide; 60 milligram per kilogram' vs 'none' in 'acetazolamide; liver' at '9 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with A.
Adjusted p-valueLog2-fold change
2.3465 × 10-31.2
Hpdl'caffeine; 100 milligram per kilogram' vs 'none' in 'caffeine; liver' at '24 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
8.3116 × 10-81.1
Hpdl'allopurinol; 15 milligram per kilogram' vs 'none' in 'allopurinol; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with A.
Adjusted p-valueLog2-fold change
1.059 × 10-6-1.1
Hpdl'erythromycin ethylsuccinate; 100 milligram per kilogram' vs 'none' in 'erythromycin ethylsuccinate; liver' at '9 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with D and E.
Adjusted p-valueLog2-fold change
1.4774 × 10-3-1.1
Hpdl'spinal cord transection' at '21 day' vs 'control' at '0 day'injury, timeTranscription profiling by array of adult rat tails following spinal cord transection
Adjusted p-valueLog2-fold change
1.2614 × 10-2-1.1
Hpdl'allopurinol; 150 milligram per kilogram' vs 'none' in 'allopurinol; kidney' at '8 day'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from repeat dosing studies: compounds starting with A.
Adjusted p-valueLog2-fold change
2.5512 × 10-21.1
Hpdl'squamous cell carcinoma' vs 'normal' in 'fibroblast'cell type, diseaseTranscription profiling by array of rat tongue epithelia and submucosal fibroblasts during oral carcinogenesis
Adjusted p-valueLog2-fold change
2.8583 × 10-2-1.1
Hpdl'female soleus muscle' vs 'male soleus muscle'organism part, sexIdentification of sexually dimorphically expressed genes in rat tissues
Adjusted p-valueLog2-fold change
6.5539 × 10-61
Hpdl'imipramine; 30 milligram per kilogram' vs 'none' in 'imipramine; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with F to I.
Adjusted p-valueLog2-fold change
7.3462 × 10-61
Hpdl'cisplatin; 3 milligram per kilogram' vs 'none' in 'cisplatin; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
1.1704 × 10-51
Hpdl'caffeine; 10 milligram per kilogram' vs 'none' in 'caffeine; liver' at '24 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
3.0474 × 10-51
Hpdl'gentamicin; 10 milligram per kilogram' vs 'none' in 'gentamicin; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with F to I.
Adjusted p-valueLog2-fold change
6.6962 × 10-5-1
Hpdl'ethionine; 80 milligram per kilogram' vs 'none' in 'ethionine; liver' at '24 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with D and E.
Adjusted p-valueLog2-fold change
1.2694 × 10-4-1
Hpdl'spinal cord transection' at '60 day' vs 'control' at '0 day'injury, timeTranscription profiling by array of adult rat tails following spinal cord transection
Adjusted p-valueLog2-fold change
4.2503 × 10-4-1
Hpdl'ciprofloxacin; 300 milligram per kilogram' vs 'none' in 'ciprofloxacin; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
5.4971 × 10-41
Hpdl'captopril; 100 milligram per kilogram' vs 'none' in 'captopril; liver' at '9 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
1.6732 × 10-31
Hpdl'captopril; 300 milligram per kilogram' vs 'none' in 'captopril; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
2.0288 × 10-31
Hpdl'bromoethylamine; 60 milligram per kilogram' vs 'none' in 'bromoethylamine; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with B.
Adjusted p-valueLog2-fold change
2.8118 × 10-3-1
Hpdl'spinal cord transection' at '2 day' vs 'control' at '0 day'injury, timeTranscription profiling by array of adult rat tails following spinal cord transection
Adjusted p-valueLog2-fold change
2.3587 × 10-21
Hpdl'thioacetamide; 45 milligram per kilogram' vs 'none' in 'thioacetamide; kidney' at '29 day'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from repeat dosing studies: compounds starting with S to T.