ENSRNOG00000040120 (Bhmt2)

rattus norvegicus

betaine-homocysteine S-methyltransferase 2

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Rattus norvegicus
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Showing 50 experiments:
image/svg+xml aorta circulatory system blood vessel brown adipose tissue white adipose tissue skin stomach duodenum pancreas spleen adrenal gland kidney colon small intestine caecum jejunum ileum esophagus gall bladder parotid gland submandibular gland lymph node parathyroid gland tongue Peyer’s patch prostate gland vas deferens epididymis testis seminal vesicle penis urinary bladder thymus femur bone marrow cartilage quadriceps femoris spinal cord lung diaphragm peripheral nervous system trachea hindlimb trigeminal nerve eye sciatic nerve intestinal mucosa liver heart brain skeletal muscle
Created with Highcharts 6.2.0adrenal glandcentral neural epitheliumepidermal ectodermileummedial nasal prominenceoviductsubmandibular glandwhole bodyaxillary lymph nodebronchuscorpora quadrigeminadiencephalonfloor plateheartkidneylungmuscle (biceps femoris)olfactory bulbpreoptic areaspinal cordtonguevagina
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49 FANTOM5 project - adult
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49 FANTOM5 project - neonate
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49 FANTOM5 project - juvenile
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49 FANTOM5 project - embryonic day 18
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49 FANTOM5 project - embryonic day 17
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9 in 3 strains - DBA/2J
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9 in 3 strains - CD1
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49 FANTOM5 project - embryonic day 15
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9 in 3 strains - C57BL/6
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49 FANTOM5 project - embryonic day 16
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14 - embryonic day 10.5
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49 FANTOM5 project - embryonic day 14
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49 FANTOM5 project - embryonic day 12
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Mammalian Kaessmann
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49 FANTOM5 project - embryonic day 13
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Vertebrates
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14 - embryonic day 9.5
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14 - embryonic day 8.5
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4 Bonthuis et al - CastEiJ
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4 Bonthuis et al - (CastEiJ X …
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4 Bonthuis et al - (C57BL/6J X …
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Fat and muscle
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Developing gut
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Sun et al., 2020 - Organism part
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Gregg et al - CAST/EiJ
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Gregg et al - C57BL/6J
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Gregg et al - (CAST/EiJ X C57BL/6J)F1
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Gregg et al - (C57BL/6J X CAST/EiJ)F1
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4 Bonthuis et al - C57BL/6J
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Mernberger et al 2019 - Organism Part
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49 FANTOM5 project - embryonic day 11
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49 FANTOM5 project - lactating adult …
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49 FANTOM5 project - embryonic day 17.5
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49 FANTOM5 project - embryonic day 14.5
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49 FANTOM5 project - embryo
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3 Soumillon et al
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4 Bonthuis et al - Idaho derived wild …
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Duda et al., 2018 - organism part - …
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Duda et al., 2018 - organism part - …
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Deshmukh et al., 2015 - organism part
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Proteomics
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Transcriptomics
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Display log2-fold change
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Log2-fold changeSpeciesGene nameComparisonExperimental variablesExperiment name
Adjusted p-valueLog2-fold change
4.9402 × 10-3-2.8
Bhmt2'allopurinol; 150 milligram per kilogram' vs 'none' in 'allopurinol; kidney' at '29 day'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from repeat dosing studies: compounds starting with A.
Adjusted p-valueLog2-fold change
1.0467 × 10-72.3
Bhmt2'collagen sandwich' at '8 day' vs 'monolayer culture' at '8 day'growth condition, timeGenome-wide gene expression profiles of primary hepatocytes in two different culture systems over an 8-day period
Adjusted p-valueLog2-fold change
2.7289 × 10-71.6
Bhmt2'collagen sandwich' at '3 day' vs 'monolayer culture' at '3 day'growth condition, timeGenome-wide gene expression profiles of primary hepatocytes in two different culture systems over an 8-day period
Adjusted p-valueLog2-fold change
1.196 × 10-4-1.4
Bhmt2'puromycin aminonucleoside; 12 milligram per kilogram' vs 'none' in 'puromycin aminonucleoside; kidney' at '29 day'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from repeat dosing studies: compounds starting with P to R.
Adjusted p-valueLog2-fold change
1.3999 × 10-2-1.4
Bhmt2'EMD; 100 micromolar' vs 'DMSO' at '72 hour'compound, timeCross-species gene expression analysis of species-specific differences in preclinical assessment of pharmaceutical compounds (rat)
Adjusted p-valueLog2-fold change
3.0803 × 10-2-1.2
Bhmt2'allopurinol; 150 milligram per kilogram' vs 'none' in 'allopurinol; kidney' at '15 day'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from repeat dosing studies: compounds starting with A.
Adjusted p-valueLog2-fold change
4.6407 × 10-11-1.1
Bhmt2'24 hour' vs '0 hour' in 'hepatocyte'cell type, timeAssessing concordance of drug-induced transcriptional response in rodent liver and cultured hepatocytes
Adjusted p-valueLog2-fold change
8.3931 × 10-4-1.1
Bhmt2'naproxen; 60 milligram per kilogram' vs 'none' in 'naproxen; liver' at '4 day'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from repeat dosing studies: compounds starting with N to O.
Adjusted p-valueLog2-fold change
3.2384 × 10-4-1
Bhmt2'methapyrilene; 100 milligram per kilogram' vs 'none' in 'methapyrilene; liver' at '29 day'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from repeat dosing studies: compounds starting with J to M.