ENSRNOG00000055236 (Gemin4)

rattus norvegicus

gem (nuclear organelle) associated protein 4

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Rattus norvegicus
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Showing 6 experiments:
image/svg+xml brain kidney adrenal medulla chromaffin cell gastrocnemius heart liver lung spleen thymus uterus testis colon
Created with Highcharts 6.2.0adrenal glandbraincolongastrocnemiusheartkidneyliverlungskeletal muscle tissuespleentestisthymusuterus
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9 Merkin - Sprague-Dawley
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11 Yu - male, elderly
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11 Yu - male, adult
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11 Yu - female, elderly
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11 Yu - female, adult
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11 Yu - female, adolescent
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Proteomics
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Transcriptomics
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Display log2-fold change
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Log2-fold changeSpeciesGene nameComparisonExperimental variablesExperiment name
Adjusted p-valueLog2-fold change
1.2207 × 10-91.2
Gemin4'48 hour' vs '0 hour' in 'hepatocyte'cell type, timeAssessing concordance of drug-induced transcriptional response in rodent liver and cultured hepatocytes
Adjusted p-valueLog2-fold change
4.5539 × 10-81.1
Gemin4'24 hour' vs '0 hour' in 'hepatocyte'cell type, timeAssessing concordance of drug-induced transcriptional response in rodent liver and cultured hepatocytes
Adjusted p-valueLog2-fold change
8.2638 × 10-7-1.1
Gemin4'puromycin aminonucleoside; 120 milligram per kilogram' vs 'none' in 'puromycin aminonucleoside; liver' at '24 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with P to R.
Adjusted p-valueLog2-fold change
1.992 × 10-5-1.1
Gemin4'caffeine; 100 milligram per kilogram' vs 'none' in 'caffeine; liver' at '24 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
5.0844 × 10-8-1
Gemin4'caffeine; 10 milligram per kilogram' vs 'none' in 'caffeine; liver' at '24 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with C.
Adjusted p-valueLog2-fold change
8.2658 × 10-6-1
Gemin4'gentamicin; 10 milligram per kilogram' vs 'none' in 'gentamicin; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with F to I.
Adjusted p-valueLog2-fold change
2.7075 × 10-31
Gemin4'ethionine; 250 milligram per kilogram' vs 'none' in 'ethionine; liver' at '29 day'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from repeat dosing studies: compounds starting with D to E.
Adjusted p-valueLog2-fold change
4.3486 × 10-31
Gemin4'ethionine; 250 milligram per kilogram' vs 'none' in 'ethionine; liver' at '3 hour'cohort, compound, organism part, timeTranscription profiling by array of rat liver and kidney after exposure to approximately 130 chemicals collected from single dose studies: compounds starting with D and E.