EMD-11953
SARS-CoV-2 S 2P trimer in complex with monovalent DARPin R2 (State 1) - Composite Map
EMD-11953
Single-particle4.2 Å
![EMD-11953](https://www.ebi.ac.uk/emdb/images/entry/EMD-11953/400_11953.gif)
Map released: 04/05/2022
Last modified: 17/08/2022
Sample Organism:
Severe acute respiratory syndrome-related coronavirus,
synthetic construct
Sample: SARS-CoV-2 S 2P trimer in complex with monovalent DARPin R2 (State 1)
Deposition Authors: Hurdiss DL
,
Drulyte I
Sample: SARS-CoV-2 S 2P trimer in complex with monovalent DARPin R2 (State 1)
Deposition Authors: Hurdiss DL
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The trispecific DARPin ensovibep inhibits diverse SARS-CoV-2 variants.
Rothenberger S
,
Hurdiss DL
,
Walser M,
Malvezzi F,
Mayor J,
Ryter S,
Moreno H,
Liechti N
,
Bosshart A,
Iss C
,
Calabro V,
Cornelius A,
Hospodarsch T,
Neculcea A,
Looser T,
Schlegel A,
Fontaine S,
Villemagne D
,
Paladino M,
Schiegg D,
Mangold S,
Reichen C,
Radom F,
Kaufmann Y,
Schaible D,
Schlegel I,
Zitt C,
Sigrist G,
Straumann M,
Wolter J,
Comby M,
Sacarcelik F,
Drulyte I
,
Lyoo H
,
Wang C,
Li W
,
Du W,
Binz HK
,
Herrup R,
Lusvarghi S
,
Neerukonda SN,
Vassell R,
Wang W,
Adler JM
,
Eschke K,
Nascimento M
,
Abdelgawad A,
Gruber AD,
Bushe J
,
Kershaw O,
Knutson CG,
Balavenkatraman KK,
Ramanathan K,
Wyler E
,
Teixeira Alves LG,
Lewis S,
Watson R,
Haeuptle MA,
Zurcher A,
Dawson KM
,
Steiner D,
Weiss CD
,
Amstutz P,
van Kuppeveld FJM,
Stumpp MT
,
Bosch BJ
,
Engler O
,
Trimpert J
(2022) Nat Biotechnol
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(2022) Nat Biotechnol