triprolidine hydrochloride monohydrate (CHEBI:32265)

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ChEBI Name	triprolidine hydrochloride monohydrate

ChEBI ID	CHEBI:32265

Definition	A hydrate that is the monohydrate form of triprolidine hydrochloride. A sedating antihistamine, it is used for the symptomatic relief of uticaria, rhinitis, and various pruritic skin disorders.

Stars	This entity has been manually annotated by the ChEBI Team.

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Formula

C19H25ClN2O

Net Charge

Average Mass

332.86800

Monoisotopic Mass

332.16554

InChI

InChI=1S/C19H22N2.ClH.H2O/c1-16-7-9-17(10-8-16)18(19-6-2-3-12-20-19)11-15-21-13-4-5-14-21;;/h2-3,6-12H,4-5,13-15H2,1H3;1H;1H2/b18-11+;;

InChIKey

CUZMOIXUFHOLLN-UMVVUDSKSA-N

SMILES

O.Cl.Cc1ccc(cc1)C(=C/CN1CCCC1)\c1ccccn1

Roles Classification
Biological Role(s):	H1-receptor antagonist H1-receptor antagonists are the drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine.

Application(s):	H1-receptor antagonist H1-receptor antagonists are the drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine.

ChEBI Ontology
Outgoing	triprolidine hydrochloride monohydrate (CHEBI:32265) has part triprolidine hydrochloride (anh.) (CHEBI:84119) triprolidine hydrochloride monohydrate (CHEBI:32265) has role H₁-receptor antagonist (CHEBI:37955) triprolidine hydrochloride monohydrate (CHEBI:32265) is a hydrate (CHEBI:35505)

IUPAC Name

2-[(1E)-1-(4-methylphenyl)-3-(pyrrolidin-1-yl)prop-1-en-1-yl]pyridine hydrochloride—water (1/1)

Synonym	Source
1-[(2E)-3-(4-methylphenyl)-3-(pyridin-2-yl)prop-2-en-1-yl]pyrrolidinium chloride—water (1/1)	IUPAC

Registry Number	Type	Source
6138-79-0	CAS Registry Number	ChemIDplus

Last Modified

17 December 2014