CHEBI:90527 - N-cyclopropyl-3-{4-[(cyclopropylmethyl)carbamoyl]phenyl}-4-methylbenzamide

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ChEBI Name N-cyclopropyl-3-{4-[(cyclopropylmethyl)carbamoyl]phenyl}-4-methylbenzamide
ChEBI ID CHEBI:90527
ChEBI ASCII Name N-cyclopropyl-3-{4-[(cyclopropylmethyl)carbamoyl]phenyl}-4-methylbenzamide
Definition A dicarboxylic acid diamide obtained by condensation of the 3- and 4'-carboxy groups of 6-methyl[1,1'-biphenyl]-3,4'-dicarboxylic acid with cyclpropylamine and cyclpropylmethylamine respectively.
Stars This entity has been manually annotated by the ChEBI Team.
Submitter Matthias Ziehm
Supplier Information
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Formula C22H24N2O2
Net Charge 0
Average Mass 348.439
Monoisotopic Mass 348.18378
InChI InChI=1S/C22H24N2O2/c1-14-2-5-18(22(26)24-19-10-11-19)12-20(14)16-6-8-17(9-7-16)21(25)23-13-15-3-4-15/h2,5-9,12,15,19H,3-4,10-11,13H2,1H3,(H,23,25)(H,24,26)
InChIKey BOPSUAHGQHFKGG-UHFFFAOYSA-N
SMILES CC1=CC=C(C(=O)NC2CC2)C=C1C3=CC=C(C=C3)C(=O)NCC4CC4
Roles Classification
Biological Role(s): EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of mitogen-activated protein kinase (EC 2.7.11.24).
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ChEBI Ontology
Outgoing N-cyclopropyl-3-{4-[(cyclopropylmethyl)carbamoyl]phenyl}-4-methylbenzamide (CHEBI:90527) has role EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor (CHEBI:79091)
N-cyclopropyl-3-{4-[(cyclopropylmethyl)carbamoyl]phenyl}-4-methylbenzamide (CHEBI:90527) is a benzamides (CHEBI:22702)
N-cyclopropyl-3-{4-[(cyclopropylmethyl)carbamoyl]phenyl}-4-methylbenzamide (CHEBI:90527) is a biphenyls (CHEBI:22888)
N-cyclopropyl-3-{4-[(cyclopropylmethyl)carbamoyl]phenyl}-4-methylbenzamide (CHEBI:90527) is a cyclopropanes (CHEBI:51454)
N-cyclopropyl-3-{4-[(cyclopropylmethyl)carbamoyl]phenyl}-4-methylbenzamide (CHEBI:90527) is a dicarboxylic acid diamide (CHEBI:35779)
IUPAC Name
N3-cyclopropyl-N4'-(cyclopropylmethyl)-6-methyl[1,1'-biphenyl]-3,4'-dicarboxamide
Manual Xrefs Databases
DB07835 DrugBank
GK5 PDBeChem
View more database links
Registry Number Type Source
18849547 Reaxys Registry Number Reaxys
Citation Waiting for Citations Type Source
18614366 PubMed citation Europe PMC
Last Modified
02 December 2015