EMD-11041

Single-particle
4.0 Å
EMD-11041
3D View Gallery
Deposition: 16/05/2020
Map released: 08/07/2020
Last modified: 22/05/2024
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links

EMD-11041
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 6z2j summary report (pdf.gz) Map and 6z2j FULL report (pdf.gz)
EMICSS annotations (xml)

The structure of the dimeric HDAC1/MIDEAS/DNTTIP1 MiDAC deacetylase complex

EMD-11041

Single-particle
4.0 Å
EMD-11041
3D View Gallery
Deposition: 16/05/2020
Map released: 08/07/2020
Last modified: 22/05/2024
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Sample Organism: Homo sapiens
Sample: Dimeric complex of the MiDAC deacetylase complex containing HDAC1, the ELM2-SANT domain of MIDEAS and the dimerisation domain of DNTTIP1
Fitted models: 6z2j

Deposition Authors: Fairall L , Saleh A
The MiDAC histone deacetylase complex is essential for embryonic development and has a unique multivalent structure.
Turnbull RE , Fairall L , Saleh A, Kelsall E, Morris KL , Ragan TJ , Savva CG, Chandru A, Millard CJ , Makarova OV, Smith CJ , Roseman AM , Fry AM, Cowley SM , Schwabe JWR
(2020) Nat Commun , 11 , 3252 - 3252
PUBMED: 32591534
DOI: doi:10.1038/s41467-020-17078-8
ISSN: 2041-1723