About EMDB
Meet the team
The Electron Microscopy Data Bank (EMDB) team operates out of EMBL-EBI and you can read more about us here.
EMDB history
The EMDB is a public repository for cryogenic-sample Electron Microscopy (cryoEM) volumes and representative tomograms of macromolecular complexes and subcellular structures. It covers a variety of techniques, including single-particle analysis, helical reconstruction, electron tomography, subtomogram averaging, and electron crystallography (for more information, see the EMDB Policies).
EMDB was founded at EMBL-EBI in 2002 under the leadership of Kim Henrick. From 2007, the archive has been operated jointly by EMBL-EBI and the Research Collaboratory for Structural Bioinformatics (RCSB)a. In 2013, the Protein Data Bank Japan (PDBj) also became involved in EMDB. As of the first of January, 2021, EMDB is an archive operated under the aegis of the Worldwide Protein Data Bank (wwPDB), and has also joined that organisation as a full member.
Results of cryo-EM studies are archived in three collaborating archives:
- EMDB stores the processed 3D volumes and tomograms;
- PDB stores any atomic models that have been constructed based on EMDB data;
- EMPIAR stores the raw EM data underpinning the data in EMDB/PDB.
Data for EMDB and PDB can be deposited through the wwPDB deposition and annotation system OneDep.
EMPIAR (Electron Microscopy Public Image Archive) is a companion archive to EMDB, founded at and operated by EMBL-EBI, and with a mirror site at PDBj.
Citing EMDB
Please cite the following publication in your papers and on websites: The wwPDB Consortium, EMDB—the Electron Microscopy Data Bank, Nucleic Acids Research, Volume 52, Issue D1, 5 January 2024, Pages D456–D465, https://doi.org/10.1093/nar/gkad1019
To cite individual entries, please quote the EMDB accession code(s) and cite the original publication(s) in which the entries are described.
EMDB logos and branding should not be used on public-facing websites unless explicit prior permission has been obtained from us. However, if you want to use an EMDB logo in a presentation or report, you can use the images in the following table royalty-free and without the need to obtain prior permission from us.
More information
Please see our FAQ, Policies, description of the EMDB data model, or contact the EMDB helpdesk.
Funding
The work on EMDB at EMBL-EBI has been funded in the past by the European Commission, NIH, UKRI-BBSRC and EMBL-EBI (through the EMBL member states). It is currently funded by the Wellcome Trust and EMBL-EBI.
Quick links
Recent Entries
(Show all)Cryo-EM structure of P. urativorans 70S ribosome after 24h acute stress - State 4: E-tRNA/RaiA/Balon
Cryo-EM (200kV) structure of pyruvate decarboxylase from Neoasaia chiangmaiensis
Cryo-EM structure of P. urativorans 70S ribosome after 72h acute stress - State 2: E-tRNA/P-tRNA/A-tRNA
Cryo-EM structure of P. urativorans 70S ribosome after 24h acute stress - State 3: E-tRNA/P-tRNA/Balon
Cryo-EM structure of human TRPM4 channel in complex with calcium and CBA at 37 degrees Celsius (monomeric TMD-focused map with best-resolved CBA density)
Structural basis of influenza A virus neutralization by broadly active single-domain antibody G2.3 recognizing glycosylated epitope within hemagglutinin stem
Cryo-EM structure of human TRPM4 channel in complex with calcium and NBA at 37 degrees Celsius (monomeric TMD-focused map with best-resolved NBA density)
Cryo-EM structure of the parainfluenza virus hemagglutinin-neuraminidase protein in complex with the human antibodies 5217-2 and PIV3HN-09
Cryo-EM structure of human TRPM4 channel in complex with EGTA and TPPO at 37 degrees Celsius (consensus)
Cryo-EM structure of human TRPM4 channel in complex with calcium and TPPO at 37 degrees Celsius (consensus)
Cryo-EM structure of the parainfluenza virus hemagglutinin-neuraminidase protein in complex with the human antibodies PIV3HN-09 and PIV3HN-13
Cryo-EM structure of human TRPM4 channel in complex with calcium and NBA at 37 degrees Celsius (consensus)
Cryo-EM structure of human TRPM4 channel in complex with calcium and CBA at 37 degrees Celsius (consensus)
Cryo-EM structure of human TRPM4 channel in complex with calcium and CBA and DVT at 37 degrees Celsius (consensus)
Cryo-EM structure of the parainfluenza virus hemagglutinin-neuraminidase protein in complex with the human antibodies PIV3HN-05 and PIV3HN-13
Cryo-EM structure of HCoV-OC43-C2 Spike glycoprotein in complex with 9O-acetyl GD3 sialoglycan
Heparin-induced trans tetrameric complex of VEGF, VEGFR2 and Neuropilin 1
Heparin-induced cis tetrameric complex of VEGF, VEGFR2 and Neuropilin 1
Cryo-EM structure of human TRPM4 channel in complex with EGTA and NC1 at 37 degrees Celsius (consensus)
Consensus map of full-length human VPS13C in complex with calmodulin
Cryo-EM structure of human TRPM4 channel in complex with calcium and TPPO at 18 degrees Celsius (consensus)
Cryo-EM structure of human TRPM4 channel in complex with calcium and NC1 at 37 degrees Celsius (consensus)
Cryo-EM structure of SULTR-like phosphate distribution transporter
Neuraminidase NA isolated from the H1N1 strain A/Victoria/2570/2019 propagated in eggs in complex with zanamivir
Cryo-EM structure of SULTR-like phosphate distribution transporter with phosphate
focused refined map; map for 40S body from human 48S PIC on Kozak mRNA (Kozak_1)
focused refined map; human eIF3 in 48S PIC on Kozak mRNA (Kozak_2)
Cryo-EM structure of the Arabidopsis thaliana 40S ribosomal subunit (Head)
Cryo-EM structure of the Arabidopsis thaliana 60S ribosomal subunit
focused refined map; 40S head with TC from human 48S PIC on mRNA (non-Kozak)
Cryo-EM structure of the Arabidopsis thaliana 40S ribosomal subunit
focused refined map; 40S head with TC from human 48S PIC on Kozak mRNA (Kozak_2)
focused refined map; 40S body with eIF1A from human 48S PIC with eIF1A W70A mutant on Kozak mRNA
focused refined map; 40S body with eIF1A from human 48S PIC on Kozak mRNA (Kozak_2)
focused refined map; 40S head with TC from human 48S PIC with eIF1A W70A mutant on Kozak mRNA
focused refined map; 40S body with eIF1A from human 48S PIC on mRNA (non-Kozak)
focused refined map; 40S head with TC from human 48S PIC on Kozak mRNA (Kozak_1)
focused refined map; human eIF3 in 48S PIC on Kozak mRNA (Kozak_1)
Heimdallarchaeales alpha/beta tubulin microtubule with three seams
Heimdallarchaeales alpha/beta tubulin microtubule with a single seam
Cryo-EM Structure of Human Protease-Activated Receptor 4 in complex with Gq heterotrimers and ScFv16 bound to Tethered Ligand
6-Helix Bundle - with a Clasp (6HB-C)-dimer with 2'-Fluoro-modified pyrimidines (FY RNA)
Composite structure of the sheathed flagellar motor in Vibrio cholerae adopting a lower FOMC conformation
Composite structure of the sheathed flagellar motor in Vibrio cholerae adopting a higher FOMC conformation
Flagellar outer membrane complex in Vibrio cholerae at disassembled, closed state
H-ring subunit FlgO and FlgP in Vibrio cholerae at assembled, opened state
RBM3 domain of FliF protein in MS-ring of flagellar motor in Vibrio cholerae
HRV14 3C in complex with single chain antibody YDF and cloverleafRNA-conformation2 splitRNA
Cryo-EM structure of AtubAB mini microtubules from Heimdallarchaeia
Integrin AlphaIIbBeta3 bound to Fab of the anti-HPA-1a antibody 26.4
cryo-EM structure of human organic solute transporter in complex with DHEAS
cryo-EM structure of human organic solute transporter in complex with TLCA
cryo-EM structure of human organic solute transporter in complex with fidaxomicin
cryo-EM structure of human organic solute transporter in apo state
cryo-EM structure of human organic solute transporter in complex with ethinylestradiol
Cryo-EM structure of AccA3/AccD4/AccD5/AccE5 in complex with Propionyl-CoA
cryo-EM structure of AccA3/AccD4/AccD5/AccE5 complex from Mycobacterium smegmatis
cryo-EM structure of AccA3-AccE5 complex in the presence of Arachidyl-CoA
AtubAB mini microtubule in situ in E. coli by subtomogram averaging
Constituent EM map: local refinement of putative MUC2 binding domain of rEatAp and Fab G12 from best Fab-containing 2D classes
Cryo-EM structure of BAM from P. aeruginosa PAO1 in complex with Pyocin L1
Constituent EM map: local refinement of putative MUC2 binding domain of rEatAp and Fv domain of Fab G12
Cryo-EM structure of BAM from P. aeruginosa P28 in complex with Pyocin L2
Cryo-EM structure of the VPS13C N-terminal region in complex with Calmodulin
Cryo-EM structure of NRAS(Q61K)-BRIL fusion in complex with Fab(BAG2) and Monobody(Mb24)
LPHT-ring subunit with C13 MotX in Vibrio cholerae at assembled state
Full-length human VPS13C in complex with calmodulin from the CryoEM composite map
A cryo-EM structure of native C3 protein in a compact conformation.
Human Mortalin (mitochondrial Hsp70) in complex with GrpE1 phosphorylated at Ser-47
Human Mortalin (mitochondrial Hsp70) in complex with wild-type GrpE1
RecA 12-monomer mini-filament bound to dsDNA with 7-nt homology at 250ms using time-resolved cryo-EM
Cryo-electron microscopy structure of nanofibers formed by reverse azobenzene peptides.
ALFA-tag-FtnA from E.Coli isolated from in vitro translation reaction
Cryo-EM structure of the aspartate:alanine antiporter AspT WT_TM_Local Refinment
Cryo-EM structure of the aspartate:alanine antiporter AspT WT Consensus map
Cryo-EM structure of the aspartate:alanine antiporter AspT WT_SD_Local refinement
Structure of choline transporter BetT with C-terminal deletion(residues 514-677 deleted)
Escherichia coli transcription-translation loosely coupled complex complex (TTC-LC^walked) containing mRNA with a 39 nt long spacer, NusG, NusA, and fMet-tRNAs in E-site and P-site - Map 1
Cryo-EM structure of avadomide-organized CRL4-DDB1-CRBN-IKZF3(ZF2-ZF3)-UbcH5a-Ub ubiquitylation assembly
Structure of SB290157 bound to human C3aR in complex with Go (Receptor Ligand Focused map)
Cryo-EM structure of two cPRC1 complexes bound to opposite faces of an endogenous 147-bp mono-nucleosome
Pseudomonas aeruginosa (PAO1) Outer membrane PilQ (Secretin) in C14 symmetry
Cryo-EM structure of pomalidomide-organized CRL4-DDB1-CRBN-IKZF3(ZF2-ZF3)-UbcH5a-Ub ubiquitylation assembly
Cryo-EM structure of cemsidomide-organized CRL4-DDB1-CRBN-IKZF3(ZF2-ZF3)-UbcH5a-Ub ubiquitylation assembly
Pseudomonas aeruginosa (PAO1) Outer membrane PilQ (Secretin) with SlkB in C14 symmetry
Pseudomonas aeruginosa (PAO1) Outer membrane PilQ (Secretin) with SlkA in C14 symmetry
Cryo-EM structure of a single cPRC1 complex engaged on one face of an endogenous 147-bp mononucleosome
Cryo-EM structure of mezigdomide-organized CRL4-DDB1-CRBN-IKZF3(ZF2-ZF3)-UbcH5a-Ub ubiquitylation assembly
Cryo-EM structure of the cPRC1-UbcH5c E3-E2 complex bound to the H2BK120ub-modified nucleosome
Pseudomonas aeruginosa (PAO1) Outer membrane PilQ (Secretin) with SlkA in C1 symmetry
Pseudomonas aeruginosa (PAO1) Outer membrane PilQ (Secretin) in C1 symmetry
Pseudomonas aeruginosa (PAO1) Outer membrane PilQ (Secretin) with SlkB in C1 symmetry
Constituent EM map: Focused refinement of NCP_1 in the cPRC1-di-nucleosome(loose) complex.
Cryo-EM structure of Borna disease virus RNA-directed RNA polymerase in complex with Suramin
Cryo-EM structure of Borna disease virus RNA polymerase L protein
Cryo-EM structure of the ncPRC1.1-UbcH5c E3-E2 complex bound to the H2BK120ub-modified nucleosome
Cryo-EM structure of the ncPRC1.6 complex bound to the H2AK119ubH2BK120ub-modified nucleosome
Cryo-EM structure of the ncPRC1.1 complex bound to the H2AK119ubH2BK120ub-modified nucleosome
Cryo-EM structure of the cPRC1 complex bound to an endogenous 184-bp mono-nucleosome
Cryo-EM structure of the ncPRC1.4 complex containing two RNF2-BMI1 bound to the H2AK119ubH2BK120ub-modified nucleosome
Constituent EM map: Focused refinement of NCP_1 in the cPRC1-di-nucleosome (tight) complex
Constituent EM map: Focused refinement of NCP_2 in the cPRC1-di-nucleosome (loose) complex
Low-resolution EM map of the cPRC1-di-nucleosome (loose) complex, used as a template for fitting high-resolution cPRC1-bound nucleosome density maps.
Constituent EM map: Focused refinement of RNF2&BMI1 bounded NCP_1 in the cPRC1-di-nucleosome (tight) complex
Constituent EM map: Focused refinement of RNF2&BMI1 bounded NCP_1 in the cPRC1-di-nucleosome(loose) complex
Constituent EM map: Focused refinement of RNF2&BMI1 bounded NCP_2 in the cPRC1-di-nucleosome (CBX7) complex
Constituent EM map: Focused refinement of NCP_1 in the cPRC1-di-nucleosome (CBX7) complex
Low-resolution EM map of the cPRC1-di-nucleosome (CBX7) complex, used as a template for fitting high-resolution cPRC1-bound nucleosome density maps
Constituent EM map: Focused refinement of NCP_2 in the cPRC1-di-nucleosome (tight) complex
Constituent EM map: Focused refinement of RNF2&BMI1 bounded NCP_2 in the cPRC1-di-nucleosome (tight) complex
Constituent EM map: Focused refinement of RNF2&BMI1 bounded NCP_1 in the cPRC1-di-nucleosome (CBX7) complex
Constituent EM map: Focused refinement of NCP_2 in the cPRC1-di-nucleosome (CBX7) complex
Low-resolution EM map of the cPRC1-di-nucleosome (tight) complex, used as a template for fitting high-resolution cPRC1-bound nucleosome density maps
Cryo-EM structure of the ncPRC1.4 complex containing one RNF2-BMI1 and one RYBP bound to the H2AK119ubH2BK120ub-modified nucleosome
Cryo-EM structure of the ncPRC1.4 complex containing one RNF2-BMI1 and one RYBP bound to the H2AK119ub-modified nucleosome
Cryo-EM structure of the ncPRC1.4 complex containing two RYBP bound to the H2AK119ub-modified nucleosome
Cryo-EM structure of the ncPRC1.4 complex containing one RYBP bound to the H2AK119ub-modified nucleosome
Cryo-EM structure of the ncPRC1.4 complex containing one RNF2-BMI1 bound to the H2AK119ub-modified nucleosome
Cryo-EM structure of P. urativorans 70S ribosome after 2h acute stress - State 3: E-tRNA/P-tRNA/Balon
Cryo-EM structure of P. urativorans 70S ribosome after 24h acute stress - State 1: Rotated with E-tRNA/P-tRNA
Cryo-EM map of influenza hemagglutinin (A/Hong Kong/1/1968, H3N2) plunged control sample
Cryo-EM map of influenza hemagglutinin (A/Hong Kong/1/1968, H3N2) following ultrasonic excitation during plunging
Cryo-EM structure of human PRMT5:MEP50 in complex with SAH and compounds 16-19F and HJL-1
Cryo-EM structure of human Wntless-Wnt5a 2:2 complex - Composite map
Cryo-EM structure of human Wntless-Wnt5a 2:2 complex - Focused map B
Cryo-EM structure of human Wntless-Wnt5a 2:2 complex - Focused map A
Cryo-EM structure of human Wntless-Wnt5a 2:2 complex - Consensus map
Escherichia coli transcription-translation loosely coupled complex (TTC-LC^walked) containing mRNA with a 39 nt long spacer, NusG, NusA, and fMet-tRNAs in E-site and P-site
Cryo-EM structure of human Wntless in complex with Wnt5a at 1:1 stoichiometry
Structure of Geobacillus stearothermophilus RNase P holoenzyme in 5 mM Mg2+
Structure of Geobacillus stearothermophilus RNase P holoenzyme in complex with precursor tRNA in 5 mM Ca2+
Structure of Geobacillus stearothermophilus RNase P ribozyme in complex with precursor tRNA with non-complementary 5' leader (sub-conformation 2 of tRNA anticodon arm tilted)
Structure of Geobacillus stearothermophilus RNase P ribozyme in complex with precursor tRNA with non-complementary 5' leader (sub-conformation 1 of tRNA anticodon arm tilted)
Consensus map of E. coli clamp loader DnaX-complex loading beta-clamp onto 10-nt gapped DNA in state 1 the DNA recognition state
Spermine-blocked open-state cryo-EM structure of human TRPV6 channel in cNW30 nanodiscs
Structure of Geobacillus stearothermophilus RNase P holoenzyme in complex with the precursor tRNA with non-complementary 5' leader
Structure of Geobacillus stearothermophilus RNase P holoenzyme in complex with precursor tRNA in 1 mM Ca2+
Structure of Geobacillus stearothermophilus RNase P holoenzyme in complex with the precursor tRNA with loop-back 5' leader (sub-conformation 1 of tRNA anticodon arm tilted)
Structure of Geobacillus stearothermophilus RNase P holoenzyme in complex with mature tRNA in 5 mM Ca2+
Structure of Geobacillus stearothermophilus RNase P holoenzyme in complex with the precursor tRNA with loop-back 5' leader (sub-conformation 2 of tRNA anticodon arm tilted)
Cryo-EM structure of the human beta2-adrenergic receptor in complex with a novel antagonist
Chlorophyll f-containing monomeric far-red Photosystem II from Calothrix sp. NIES-3974
Chlorophyll f-containing dimeric far-red Photosystem II from Chroococcidiopsis thermalis PCC 7203
Composite map of Type II-A CRISPR integrase prespacer catching complex, State II
Cryo-EM structure of P. urativorans 70S ribosome after 72h acute stress - State 1: Rotated with E-tRNA/P-tRNA




