EMD-13058

Single-particle
2.9 Å
EMD-13058
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Deposition: 10/06/2021
Map released: 11/05/2022
Last modified: 24/04/2024
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EMD-13058
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Cryo-EM structure of an Escherichia coli 70S ribosome in complex with elongation factor G and the antibiotic Argyrin B

EMD-13058

Single-particle
2.9 Å
EMD-13058
3D View Gallery
Deposition: 10/06/2021
Map released: 11/05/2022
Last modified: 24/04/2024
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Sample Organism: Escherichia coli BL21(DE3)
Sample: Cryo-EM structure of an Escherichia coli 70S ribosome in complex with elongation factor G and the antibiotic ArgyrinB
Fitted models: 7otc

Deposition Authors: Wieland M , Koller TO
The cyclic octapeptide antibiotic argyrin B inhibits translation by trapping EF-G on the ribosome during translocation.
Wieland M , Holm M, Rundlet EJ , Morici M , Koller TO , Maviza TP , Pogorevc D, Osterman IA , Muller R , Blanchard SC , Wilson DN
(2022) PNAS , 119 , e2114214119 - e2114214119
PUBMED: 35500116
DOI: doi:10.1073/pnas.2114214119
ISSN: 1091-6490
ASTM: PNASA6