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EMD-13156

Single-particle
3.58 Å
EMD-13156 Deposition: 01/07/2021
Map released: 08/12/2021
Last modified: 13/11/2024
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links

EMD-13156

Cryo-EM structure of HIV-1 reverse transcriptase with a DNA aptamer in complex with fragment F04 at the transient P-pocket

EMD-13156

Single-particle
3.58 Å
EMD-13156 Deposition: 01/07/2021
Map released: 08/12/2021
Last modified: 13/11/2024
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Sample Organism: Human immunodeficiency virus type 1 BH10, synthetic construct
Sample: Cryo-EM structure of HIV-1 reverse transcriptase with a DNA aptamer in complex with fragment F04 at the transient P-pocket
Fitted models: 7p15

Deposition Authors: Singh AK , Das K
Sliding of HIV-1 reverse transcriptase over DNA creates a transient P pocket - targeting P-pocket by fragment screening.
Singh AK , Martinez SE, Gu W , Nguyen H , Schols D, Herdewijn P, De Jonghe S , Das K
(2021) Nat Commun , 12 , 7127 - 7127
PUBMED: 34880240
DOI: doi:10.1038/s41467-021-27409-y
ISSN: 2041-1723