EMD-15681

Single-particle
6.45 Å
EMD-15681
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Deposition: 26/08/2022
Map released: 05/04/2023
Last modified: 20/11/2024
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links

EMD-15681
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8avf summary report (pdf.gz) Map and 8avf FULL report (pdf.gz)
EMICSS annotations (xml)

Human leptin in complex with the human LEP-R ectodomain fused to a C-terminal trimeric isoleucine GCN4 zipper (closed 3:3 model)

EMD-15681

Single-particle
6.45 Å
EMD-15681
3D View Gallery
Deposition: 26/08/2022
Map released: 05/04/2023
Last modified: 20/11/2024
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Sample Organism: Homo sapiens
Sample: Human leptin in complex with the human LEP-R ectodomain C-terminally fused to a trimeric GCN4 isoleucine zipper tag
Fitted models: 8avf

Deposition Authors: Verstraete K , Savvides SN , Verschueren KG, Tsirigotaki A
Mechanism of receptor assembly via the pleiotropic adipokine Leptin.
Tsirigotaki A, Dansercoer A, Verschueren KHG, Markovic I , Pollmann C , Hafer M, Felix J , Birck C , Van Putte W , Catteeuw D, Tavernier J , Fernando Bazan J, Piehler J , Savvides SN , Verstraete K
(2023) Nat Struct Mol Biol , 30 , 551 - 563
PUBMED: 36959263
DOI: doi:10.1038/s41594-023-00941-9
ISSN: 1545-9985