EMD-16022

Helical reconstruction
2.8 Å
EMD-16022
3D View Gallery
Deposition: 27/10/2022
Map released: 18/01/2023
Last modified: 31/01/2024
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links

EMD-16022
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8bfz summary report (pdf.gz) Map and 8bfz FULL report (pdf.gz)
EMICSS annotations (xml)

Amyloid-beta 42 filaments extracted from the human brain with Arctic mutation (E22G) of Alzheimer's disease | ABeta42

EMD-16022

Helical reconstruction
2.8 Å
EMD-16022
3D View Gallery
Deposition: 27/10/2022
Map released: 18/01/2023
Last modified: 31/01/2024
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Sample Organism: Homo sapiens
Sample: Amyloid-beta 42 dimeric filaments extracted from the human brain with Arctic mutation (E22G) of Alzheimer's disease
Fitted models: 8bfz

Deposition Authors: Yang Y, Zhang WJ, Murzin AG, Schweighauser M, Huang M , Lovestam SKA, Peak-Chew SY, Macdonald J, Lavenir I, Ghetti B, Graff C , Kumar A, Nordberg A, Goedert M, Scheres SHW
Cryo-EM structures of amyloid-beta filaments with the Arctic mutation (E22G) from human and mouse brains.
Yang Y, Zhang W , Murzin AG, Schweighauser M, Huang M , Lovestam S, Peak-Chew SY, Saito T , Saido TC, Macdonald J, Lavenir I, Ghetti B, Graff C , Kumar A, Nordberg A, Goedert M, Scheres SHW
(2023) Acta Neuropathol , 145 , 325 - 333
PUBMED: 36611124
DOI: doi:10.1007/s00401-022-02533-1
ISSN: 1432-0533