EMD-17578

Single-particle
4.3 Å
EMD-17578
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Deposition: 06/06/2023
Map released: 27/09/2023
Last modified: 27/09/2023
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Overview 3D View Sample Experiment Validation Volume Browser Additional data Links

EMD-17578
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3D volume (map.gz) Experimental metadata (xml)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8p9y summary report (pdf.gz) Map and 8p9y FULL report (pdf.gz)
EMICSS annotations (xml)

SARS-CoV-2 S protein S:D614G mutant in 3-down with binding site of an entry inhibitor

EMD-17578

Single-particle
4.3 Å
EMD-17578
3D View Gallery
Deposition: 06/06/2023
Map released: 27/09/2023
Last modified: 27/09/2023
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Sample Organism: Severe acute respiratory syndrome coronavirus 2
Sample: Spike glycoprotein - Severe acute respiratory syndrome coronavirus 2
Fitted models: 8p9y

Deposition Authors: Adhav A , Forcada-Nadal A , Marco-Marin C, Lopez-Redondo ML, Llacer JL
C-2 Thiophenyl Tryptophan Trimers Inhibit Cellular Entry of SARS-CoV-2 through Interaction with the Viral Spike (S) Protein.
Gargantilla M , Frances C , Adhav A , Forcada-Nadal A , Martinez-Gualda B, Marti-Mari O , Lopez-Redondo ML, Melero R, Marco-Marin C, Gougeard N , Espinosa C , Rubio-Del-Campo A , Ruiz-Partida R, Hernandez-Sierra MDP , Villamayor-Belinchon L , Bravo J , Llacer JL , Marina A , Rubio V, San-Felix A , Geller R , Perez-Perez MJ
(2023) J Med Chem , 66 , 10432 - 10457
PUBMED: 37471688
DOI: doi:10.1021/acs.jmedchem.3c00576
ISSN: 0022-2623
ASTM: JMCMAR