EMD-18592

Single-particle
2.9 Å
EMD-18592
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Deposition: 04/10/2023
Map released: 19/06/2024
Last modified: 03/07/2024
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links

EMD-18592
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8qqi summary report (pdf.gz) Map and 8qqi FULL report (pdf.gz)
EMICSS annotations (xml)

E.coli DNA gyrase in complex with 217 bp substrate DNA and LEI-800

EMD-18592

Single-particle
2.9 Å
EMD-18592
3D View Gallery
Deposition: 04/10/2023
Map released: 19/06/2024
Last modified: 03/07/2024
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Sample Organism: Escherichia coli, Escherichia phage Mu
Sample: Ternary complex of E.coli DNA gyrase with 217 bp linear dsDNA fragment and LEI-800
Fitted models: 8qqi

Deposition Authors: Ghilarov D , Martin NI , van der Stelt M
Discovery of isoquinoline sulfonamides as allosteric gyrase inhibitors with activity against fluoroquinolone-resistant bacteria.
Bakker AT, Kotsogianni I , Avalos M , Punt JM , Liu B, Piermarini D, Gagestein B, Slingerland CJ , Zhang L, Willemse JJ , Ghimire LB , van den Berg RJHBN, Janssen APA , Ottenhoff THM , van Boeckel CAA, van Wezel GP , Ghilarov D , Martin NI , van der Stelt M
(2024) Nat Chem
PUBMED: 38898213
DOI: doi:10.1038/s41557-024-01516-x
ISSN: 1755-4349