EMD-18915

Single-particle
3.44 Å
EMD-18915
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Deposition: 16/11/2023
Map released: 21/02/2024
Last modified: 17/04/2024
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links

EMD-18915
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8r5h summary report (pdf.gz) Map and 8r5h FULL report (pdf.gz)
EMICSS annotations (xml)

Ubiquitin ligation to neosubstrate by a cullin-RING E3 ligase & Cdc34: NEDD8-CUL2-RBX1-ELOB/C-VHL-MZ1 with trapped UBE2R2~donor UB-BRD4 BD2

EMD-18915

Single-particle
3.44 Å
EMD-18915
3D View Gallery
Deposition: 16/11/2023
Map released: 21/02/2024
Last modified: 17/04/2024
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Sample Organism: Homo sapiens
Sample: Ubiquitin ligation to neosubstrate by a cullin-RING E3 ligase and Cdc34: NEDD8-CUL2-RBX1-ELOB/C-VHL-MZ1 with trapped UBE2R2~donor UB-BRD4 BD2
Fitted models: 8r5h

Deposition Authors: Liwocha J , Prabu JR , Kleiger G, Schulman BA
Cullin-RING ligases employ geometrically optimized catalytic partners for substrate targeting.
Li J , Purser N, Liwocha J , Scott DC, Byers HA, Steigenberger B, Hill S, Tripathi-Giesgen I, Hinkle T, Hansen FM, Prabu JR , Radhakrishnan SK, Kirkpatrick DS, Reichermeier KM, Schulman BA , Kleiger G
(2024) Mol Cell , 84 , 1304
PUBMED: 38382526
DOI: doi:10.1016/j.molcel.2024.01.022
ISSN: 1097-2765
ASTM: MOCEFL