EMD-21994

Single-particle
2.5 Å
EMD-21994
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Deposition: 18/05/2020
Map released: 09/09/2020
Last modified: 02/12/2020
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links

EMD-21994
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3D volume (map.gz) Experimental metadata (xml)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 6x1a summary report (pdf.gz) Map and 6x1a FULL report (pdf.gz)
EMICSS annotations (xml)

Non peptide agonist PF-06882961, bound to Glucagon-Like peptide-1 (GLP-1) Receptor

EMD-21994

Single-particle
2.5 Å
EMD-21994
3D View Gallery
Deposition: 18/05/2020
Map released: 09/09/2020
Last modified: 02/12/2020
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Sample Organism: Homo sapiens, Lama glama
Sample: PF-06882961:GLP-1R:Gs Complex
Fitted models: 6x1a

Deposition Authors: Belousoff MJ, Zhang X, Danev R
Differential GLP-1R Binding and Activation by Peptide and Non-peptide Agonists.
Zhang X , Belousoff MJ , Zhao P, Kooistra AJ , Truong TT, Ang SY , Underwood CR, Egebjerg T, Senel P, Stewart GD , Liang YL, Glukhova A , Venugopal H , Christopoulos A, Furness SGB , Miller LJ, Reedtz-Runge S, Langmead CJ , Gloriam DE , Danev R, Sexton PM, Wootten D
(2020) Mol. Cell , 80 , 485
PUBMED: 33027691
DOI: doi:10.1016/j.molcel.2020.09.020
ISSN: 1097-2765
ASTM: MOCEFL