EMD-22493
Cryo-EM structure of SKF-81297-bound dopamine receptor 1 in complex with Gs protein
EMD-22493
Single-particle3.0 Å
Deposition: 20/08/2020Map released: 24/02/2021
Last modified: 03/03/2021
Sample Organism:
Homo sapiens,
synthetic construct
Sample: SKF-81297-bound dopamine receptor 1 in complex with Gi protein
Fitted models: 7jv5
Deposition Authors: Zhuang Y, Xu P, Mao C, Wang L, Krumm B, Zhou XE, Huang S, Liu H, Cheng X, Huang X-P, Sheng D-D, Xu T, Liu Y-F, Wang Y, Guo J, Jiang Y, Jiang H, Melcher K, Roth BL, Zhang Y, Zhang C, Xu HE
Sample: SKF-81297-bound dopamine receptor 1 in complex with Gi protein
Fitted models: 7jv5
Deposition Authors: Zhuang Y, Xu P, Mao C, Wang L, Krumm B, Zhou XE, Huang S, Liu H, Cheng X, Huang X-P, Sheng D-D, Xu T, Liu Y-F, Wang Y, Guo J, Jiang Y, Jiang H, Melcher K, Roth BL, Zhang Y, Zhang C, Xu HE
Structural insights into the human D1 and D2 dopamine receptor signaling complexes.
Zhuang Y 
,
Xu P,
Mao C ,
Wang L,
Krumm B,
Zhou XE,
Huang S,
Liu H,
Cheng X ,
Huang XP,
Shen DD,
Xu T,
Liu YF,
Wang Y,
Guo J,
Jiang Y,
Jiang H,
Melcher K ,
Roth BL,
Zhang Y,
Zhang C,
Xu HE
(2021) Cell , 184 , 931 - 942.e18
,
Xu P,
Mao C ,
Wang L,
Krumm B,
Zhou XE,
Huang S,
Liu H,
Cheng X ,
Huang XP,
Shen DD,
Xu T,
Liu YF,
Wang Y,
Guo J,
Jiang Y,
Jiang H,
Melcher K ,
Roth BL,
Zhang Y,
Zhang C,
Xu HE
(2021) Cell , 184 , 931 - 942.e18