EMD-22668
SARS-CoV-2 spike in complex with the S2E12 neutralizing antibody Fab fragment
EMD-22668
Single-particle3.3 Å
Deposition: 15/09/2020Map released: 07/10/2020
Last modified: 02/12/2020
Sample Organism:
Severe acute respiratory syndrome coronavirus 2,
Homo sapiens
Sample: SARS-CoV-2 spike in complex with the S2E12 neutralizing antibody Fab fragment
Fitted models: 7k4n
Deposition Authors: Tortorici M, Veesler D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Sample: SARS-CoV-2 spike in complex with the S2E12 neutralizing antibody Fab fragment
Fitted models: 7k4n
Deposition Authors: Tortorici M, Veesler D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Ultrapotent human antibodies protect against SARS-CoV-2 challenge via multiple mechanisms.
Tortorici MA 
,
Beltramello M ,
Lempp FA,
Pinto D,
Dang HV ,
Rosen LE ,
McCallum M ,
Bowen J ,
Minola A,
Jaconi S,
Zatta F ,
De Marco A ,
Guarino B ,
Bianchi S ,
Lauron EJ,
Tucker H ,
Zhou J ,
Peter A ,
Havenar-Daughton C ,
Wojcechowskyj JA ,
Case JB ,
Chen RE,
Kaiser H ,
Montiel-Ruiz M ,
Meury M ,
Czudnochowski N ,
Spreafico R ,
Dillen J ,
Ng C ,
Sprugasci N ,
Culap K ,
Benigni F ,
Abdelnabi R ,
Foo SC ,
Schmid MA ,
Cameroni E ,
Riva A ,
Gabrieli A ,
Galli M ,
Pizzuto MS ,
Neyts J ,
Diamond MS ,
Virgin HW ,
Snell G ,
Corti D,
Fink K ,
Veesler D
(2020) Science , 370 , 950 - 957
,
Beltramello M ,
Lempp FA,
Pinto D,
Dang HV ,
Rosen LE ,
McCallum M ,
Bowen J ,
Minola A,
Jaconi S,
Zatta F ,
De Marco A ,
Guarino B ,
Bianchi S ,
Lauron EJ,
Tucker H ,
Zhou J ,
Peter A ,
Havenar-Daughton C ,
Wojcechowskyj JA ,
Case JB ,
Chen RE,
Kaiser H ,
Montiel-Ruiz M ,
Meury M ,
Czudnochowski N ,
Spreafico R ,
Dillen J ,
Ng C ,
Sprugasci N ,
Culap K ,
Benigni F ,
Abdelnabi R ,
Foo SC ,
Schmid MA ,
Cameroni E ,
Riva A ,
Gabrieli A ,
Galli M ,
Pizzuto MS ,
Neyts J ,
Diamond MS ,
Virgin HW ,
Snell G ,
Corti D,
Fink K ,
Veesler D
(2020) Science , 370 , 950 - 957