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EMD-22740
CryoEM reconstruction of SARS-CoV-2 Spike in complex with the Fab fragment of neutralizing antibody 298
EMD-22740
Single-particle6.2 Å
Deposition: 28/09/2020Map released: 28/10/2020
Last modified: 28/07/2021
Sample Organism:
Homo sapiens,
Severe acute respiratory syndrome coronavirus 2
Sample: SARS-CoV-2 Spike in complex with the Fab fragment of neutralizing antibody 298
Deposition Authors: Kucharska I, Tan YZ, Benlekbir S, Rubinstein JL, Julien JP
Sample: SARS-CoV-2 Spike in complex with the Fab fragment of neutralizing antibody 298
Deposition Authors: Kucharska I, Tan YZ, Benlekbir S, Rubinstein JL, Julien JP
Multivalency transforms SARS-CoV-2 antibodies into ultrapotent neutralizers.
Rujas E 
,
Kucharska I ,
Tan YZ ,
Benlekbir S,
Cui H,
Zhao T,
Wasney GA,
Budylowski P,
Guvenc F ,
Newton JC,
Sicard T,
Semesi A,
Muthuraman K,
Nouanesengsy A,
Aschner CB ,
Prieto K,
Bueler SA,
Youssef S,
Liao-Chan S,
Glanville J,
Christie-Holmes N,
Mubareka S,
Gray-Owen SD ,
Rubinstein JL ,
Treanor B ,
Julien JP
(2021) Nat Commun , 12 , 3661 - 3661
,
Kucharska I ,
Tan YZ ,
Benlekbir S,
Cui H,
Zhao T,
Wasney GA,
Budylowski P,
Guvenc F ,
Newton JC,
Sicard T,
Semesi A,
Muthuraman K,
Nouanesengsy A,
Aschner CB ,
Prieto K,
Bueler SA,
Youssef S,
Liao-Chan S,
Glanville J,
Christie-Holmes N,
Mubareka S,
Gray-Owen SD ,
Rubinstein JL ,
Treanor B ,
Julien JP
(2021) Nat Commun , 12 , 3661 - 3661