EMD-22943

Single-particle
3.85 Å
EMD-22943
3D View Gallery
Deposition: 04/11/2020
Map released: 16/12/2020
Last modified: 13/11/2024
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links

EMD-22943
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7kne summary report (pdf.gz) Map and 7kne FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of single ACE2-bound SARS-CoV-2 trimer spike at pH 5.5

EMD-22943

Single-particle
3.85 Å
EMD-22943
3D View Gallery
Deposition: 04/11/2020
Map released: 16/12/2020
Last modified: 13/11/2024
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Sample Organism: Severe acute respiratory syndrome coronavirus 2, Homo sapiens
Sample: Single ACE2-bound SARS-CoV-2 trimer spike at pH 5.5
Fitted models: 7kne

Deposition Authors: Gorman J , Rapp M
Cryo-EM Structures of SARS-CoV-2 Spike without and with ACE2 Reveal a pH-Dependent Switch to Mediate Endosomal Positioning of Receptor-Binding Domains.
Zhou T , Tsybovsky Y, Gorman J , Rapp M, Cerutti G , Chuang GY, Katsamba PS , Sampson JM , Schon A, Bimela J, Boyington JC, Nazzari A, Olia AS, Shi W, Sastry M, Stephens T, Stuckey J, Teng IT, Wang P, Wang S, Zhang B, Friesner RA, Ho DD, Mascola JR, Shapiro L, Kwong PD
(2020) Cell Host Microbe , 28 , 867 - 879.e5
PUBMED: 33271067
DOI: doi:10.1016/j.chom.2020.11.004
ISSN: 1934-6069