EMD-23391

Single-particle
3.2 Å
EMD-23391
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Deposition: 28/01/2021
Map released: 03/03/2021
Last modified: 12/05/2021
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links

EMD-23391
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Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7ljd summary report (pdf.gz) Map and 7ljd FULL report (pdf.gz)
EMICSS annotations (xml)

Allosteric modulator LY3154207 binding to dopamine-bound dopamine receptor 1 in complex with miniGs protein

EMD-23391

Single-particle
3.2 Å
EMD-23391
3D View Gallery
Deposition: 28/01/2021
Map released: 03/03/2021
Last modified: 12/05/2021
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Sample Organism: Homo sapiens, Rattus norvegicus, Bos taurus, Lama glama
Sample: LY3154207 and dopamine-bound dopamine receptor 1 in complex with Gs protein
Fitted models: 7ljd

Deposition Authors: Zhuang Y, Krumm B, Zhang H, Zhou XE, Wang Y, Guo J, Huang X-P, Liu Y, Wang L, Cheng X, Jiang Y, Jiang H, Melcher K, Zhang C, Yi W, Roth BL, Zhang Y, Xu HE
Mechanism of dopamine binding and allosteric modulation of the human D1 dopamine receptor.
Zhuang Y , Krumm B , Zhang H, Zhou XE, Wang Y, Huang XP, Liu Y , Cheng X , Jiang Y, Jiang H , Zhang C , Yi W, Roth BL , Zhang Y , Xu HE
(2021) Cell Res , 31 , 593 - 596
PUBMED: 33750903
DOI: doi:10.1038/s41422-021-00482-0
ISSN: 1001-0602