EMD-23519
Cryo-EM map of DH898.1 Fab-dimer bound near the CD4 binding site of HIV-1 Env CH848 SOSIP trimer
EMD-23519
Single-particle4.7 Å
Deposition: 21/02/2021Map released: 17/03/2021
Last modified: 09/06/2021
Sample Organism:
Human immunodeficiency virus 1,
Homo sapiens,
Simian-Human immunodeficiency virus
Sample: Cryo-EM structure of DH898.1 Fab-dimer bound near the CD4 binding site of HIV-1 Env CH848 SOSIP trimer.
Fitted models: 7lua
Deposition Authors: Edwards RJ, Manne K, Acharya P
Sample: Cryo-EM structure of DH898.1 Fab-dimer bound near the CD4 binding site of HIV-1 Env CH848 SOSIP trimer.
Fitted models: 7lua
Deposition Authors: Edwards RJ, Manne K, Acharya P
Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies.
Williams WB,
Meyerhoff RR 
,
Edwards RJ ,
Li H,
Manne K ,
Nicely NI ,
Henderson R,
Zhou Y ,
Janowska K,
Mansouri K ,
Gobeil S,
Evangelous T,
Hora B,
Berry M,
Abuahmad AY,
Sprenz J,
Deyton M,
Stalls V ,
Kopp M,
Hsu AL,
Borgnia MJ,
Stewart-Jones GBE,
Lee MS,
Bronkema N,
Moody MA,
Wiehe K,
Bradley T,
Alam SM,
Parks RJ,
Foulger A,
Oguin T ,
Sempowski GD ,
Bonsignori M,
LaBranche CC,
Montefiori DC,
Seaman M,
Santra S,
Perfect J,
Francica JR,
Lynn GM,
Aussedat B,
Walkowicz WE,
Laga R,
Kelsoe G ,
Saunders KO,
Fera D,
Kwong PD,
Seder RA,
Bartesaghi A,
Shaw GM,
Acharya P ,
Haynes BF
(2021) Cell , 184 , 2955
,
Edwards RJ ,
Li H,
Manne K ,
Nicely NI ,
Henderson R,
Zhou Y ,
Janowska K,
Mansouri K ,
Gobeil S,
Evangelous T,
Hora B,
Berry M,
Abuahmad AY,
Sprenz J,
Deyton M,
Stalls V ,
Kopp M,
Hsu AL,
Borgnia MJ,
Stewart-Jones GBE,
Lee MS,
Bronkema N,
Moody MA,
Wiehe K,
Bradley T,
Alam SM,
Parks RJ,
Foulger A,
Oguin T ,
Sempowski GD ,
Bonsignori M,
LaBranche CC,
Montefiori DC,
Seaman M,
Santra S,
Perfect J,
Francica JR,
Lynn GM,
Aussedat B,
Walkowicz WE,
Laga R,
Kelsoe G ,
Saunders KO,
Fera D,
Kwong PD,
Seder RA,
Bartesaghi A,
Shaw GM,
Acharya P ,
Haynes BF
(2021) Cell , 184 , 2955