EMD-23949

Single-particle
3.4 Å
EMD-23949
3D View Gallery
Deposition: 06/05/2021
Map released: 16/03/2022
Last modified: 29/03/2023
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links

EMD-23949
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3D volume (map.gz) Experimental metadata (xml)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7mqo summary report (pdf.gz) Map and 7mqo FULL report (pdf.gz)
EMICSS annotations (xml)

The insulin receptor ectodomain in complex with a venom hybrid insulin analog - "head" region

EMD-23949

Single-particle
3.4 Å
EMD-23949
3D View Gallery
Deposition: 06/05/2021
Map released: 16/03/2022
Last modified: 29/03/2023
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Sample Organism: Homo sapiens
Sample: Insulin receptor ectodomain in complex with insulin analog Vh-Ins-HSLQ - focused refinement.
Fitted models: 7mqo

Deposition Authors: Blakely AD , Xiong X , Kim JH, Menting J, Schafer IB , Schubert HL, Agrawal R, Gutmann T , Delaine C, Zhang Y, Artik GO , Merriman A, Eckert D, Lawrence MC , Coskun U , Fisher SJ, Forbes BE , Safavi-Hemami H , Hill CP , Chou DHC
Symmetric and asymmetric receptor conformation continuum induced by a new insulin.
Xiong X , Blakely A , Kim JH, Menting JG, Schafer IB , Schubert HL, Agrawal R, Gutmann T , Delaine C, Zhang YW , Artik GO , Merriman A, Eckert D, Lawrence MC , Coskun U , Fisher SJ, Forbes BE , Safavi-Hemami H , Hill CP , Chou DH
(2022) Nat Chem Biol , 18 , 511 - 519
PUBMED: 35289328
DOI: doi:10.1038/s41589-022-00981-0
ISSN: 1552-4469