EMD-24273

Single-particle
3.0 Å
EMD-24273
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Deposition: 21/06/2021
Map released: 23/03/2022
Last modified: 05/06/2024
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links

EMD-24273
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7nal summary report (pdf.gz) Map and 7nal FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of activated human SARM1 in complex with NMN and 1AD (ARM and SAM domains)

EMD-24273

Single-particle
3.0 Å
EMD-24273
3D View Gallery
Deposition: 21/06/2021
Map released: 23/03/2022
Last modified: 05/06/2024
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Sample Organism: Homo sapiens
Sample: human SARM1 in complex with NMN and 1AD
Fitted models: 7nal

Deposition Authors: Kerry PS, Nanson JD
Structural basis of SARM1 activation, substrate recognition, and inhibition by small molecules.
Shi Y , Kerry PS, Nanson JD , Bosanac T, Sasaki Y, Krauss R, Saikot FK , Adams SE, Mosaiab T, Masic V, Mao X, Rose F, Vasquez E, Furrer M, Cunnea K, Brearley A, Gu W, Luo Z, Brillault L, Landsberg MJ , DiAntonio A, Kobe B , Milbrandt J, Hughes RO, Ve T
(2022) Mol Cell , 82 , 1643
PUBMED: 35334231
DOI: doi:10.1016/j.molcel.2022.03.007
ISSN: 1097-2765
ASTM: MOCEFL