EMD-25658

Single-particle
6.6 Å
EMD-25658
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Deposition: 07/12/2021
Map released: 28/12/2022
Last modified: 17/01/2024
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Overview 3D View Sample Experiment Validation Volume Browser Additional data Links

EMD-25658
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Local refinement of the C-terminal Half of Leucine Rich Repeat Kinase 2 (LRRK2) (I2020T) bound to 11-protofilament microtubule in presence of MLi-2 kinase inhibitor

EMD-25658

Single-particle
6.6 Å
EMD-25658
3D View Gallery
Deposition: 07/12/2021
Map released: 28/12/2022
Last modified: 17/01/2024
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Sample Organism: Bos taurus, Homo sapiens
Sample: LRRK2RCKW filament bound to a 11-pf microtubule with MLi-2 present

Deposition Authors: Matyszewski M , Leschziner AE
Structural basis for Parkinson's disease-linked LRRK2's binding to microtubules.
Snead DM, Matyszewski M , Dickey AM , Lin YX, Leschziner AE , Reck-Peterson SL
(2022) Nat Struct Mol Biol , 29 , 1196 - 1207
PUBMED: 36510024
DOI: doi:10.1038/s41594-022-00863-y
ISSN: 1545-9985