EMDB < EMD-25848

EMBL

was set up in 1974 as Europe’s flagship laboratory for the life sciences – an intergovernmental organisation with more than 80 independent research groups covering the spectrum of molecular biology:

Research:

perform basic research in molecular biology

Services:

offer vital services to scientists in the member states

Training

scientists, students and visitors at all levels

Transfer

and development of technology

Develop

new instruments and methods

Integrating

life science research in Europe

More about EMBL

Six sites

represent EMBL in Europe.

Barcelona

Tissue biology and disease modelling

Grenoble

Structural biology

Hamburg

Structural biology

Heidelberg

Main laboratory

Hinxton

EMBL-EBI: European Bioinformatics Institute

Rome

Epigenetics and neurobiology

EMD-25848

Single-particle
2.97 Å

EMD-25848

3D View Gallery

Deposition: 05/01/2022
Map released: 10/08/2022
Last modified: 28/02/2024

Overview 3D View Sample Experiment Validation Volume Browser Additional data Links

Overview 3D View Sample Experiment Validation Volume Browser Additional data Links

EMD-25848

Download

Cryo-EM structure of the 20S Alpha 3 Deletion proteasome core particle in complex with FUB1

EMD-25848

Single-particle
2.97 Å
EMD-25848

EMD-25848

3D View Gallery

Deposition: 05/01/2022
Map released: 10/08/2022
Last modified: 28/02/2024

Overview 3D View Sample Experiment Validation Volume Browser Additional data Links

Sample Organism: Saccharomyces cerevisiae S288C
Sample: 20S proteasome from alpha3delta proteasome mutant in complex with Silencing boundary-establishment protein FUB1
Fitted models: 7teo

Deposition Authors: Walsh Jr RM , Rawson S

Yeast PI31 inhibits the proteasome by a direct multisite mechanism.

Rawson S , Walsh Jr RM , Velez B , Schnell HM , Jiao F, Blickling M, Ang J, Bhanu MK, Huang L , Hanna J
(2022) Nat Struct Mol Biol , 29 , 791 - 800

PUBMED: 35927584
DOI: doi:10.1038/s41594-022-00808-5
ISSN: 1545-9985

Field: