EMD-26278
TMEM106B(120-254) singlet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type B case 2 (case 7).
EMD-26278
Helical reconstruction3.0 Å
![EMD-26278](https://www.ebi.ac.uk/emdb/images/entry/EMD-26278/400_26278.gif)
Map released: 23/03/2022
Last modified: 27/04/2022
Sample Organism:
Homo sapiens
Sample: TMEM106B(120-254) singlet amyloid fibril from dementia with Lewy bodies (DLB).
Fitted models: 7u15
Deposition Authors: Fitzpatrick AWP, Stowell MHB, Chang A
,
Xiang X
,
Wang J,
Lee C,
Arakhamia T,
Simjanoska M,
Wang C,
Carlomagno Y,
Zhang G,
Dhingra S,
Thierry M,
Perneel J
,
Heeman B
,
Forgrave LM,
DeTure M,
DeMarco ML
,
Cook CN,
Rademakers R,
Dickson D,
Petrucelli L,
Mackenzie IRA
Sample: TMEM106B(120-254) singlet amyloid fibril from dementia with Lewy bodies (DLB).
Fitted models: 7u15
Deposition Authors: Fitzpatrick AWP, Stowell MHB, Chang A
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Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases.
Chang A
,
Xiang X
,
Wang J,
Lee C,
Arakhamia T,
Simjanoska M,
Wang C,
Carlomagno Y,
Zhang G,
Dhingra S,
Thierry M,
Perneel J
,
Heeman B
,
Forgrave LM,
DeTure M,
DeMarco ML
,
Cook CN,
Rademakers R,
Dickson DW,
Petrucelli L,
Stowell MHB,
Mackenzie IRA,
Fitzpatrick AWP
(2022) Cell , 185 , 1346 - 1355.e15
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![](http://www.ebi.ac.uk/web_guidelines/images/logos/orcid/orcid_16x16.png)
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![](http://www.ebi.ac.uk/web_guidelines/images/logos/orcid/orcid_16x16.png)
(2022) Cell , 185 , 1346 - 1355.e15