EMD-26443

Single-particle
3.5 Å
EMD-26443
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Deposition: 16/03/2022
Map released: 17/08/2022
Last modified: 07/09/2022
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links

EMD-26443
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3D volume (map.gz) Experimental metadata (xml)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7ucg summary report (pdf.gz) Map and 7ucg FULL report (pdf.gz)
EMICSS annotations (xml)

Structure of the DU422 SOSIP.664 trimer in complex with neutralizing antibody Fab fragments 10-1074 and BG24

EMD-26443

Single-particle
3.5 Å
EMD-26443
3D View Gallery
Deposition: 16/03/2022
Map released: 17/08/2022
Last modified: 07/09/2022
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Sample Organism: Homo sapiens, Human immunodeficiency virus 1
Sample: Complex of DU422 SOSIP trimer bound to 10-1074 and BG24 Fab fragments
Fitted models: 7ucg

Deposition Authors: Barnes CO , Bjorkman PJ
A naturally arising broad and potent CD4-binding site antibody with low somatic mutation.
Barnes CO , Schoofs T , Gnanapragasam PNP, Golijanin J, Huey-Tubman KE, Gruell H , Schommers P , Suh-Toma N, Lee YE , Cetrulo Lorenzi JC , Piechocka-Trocha A , Scheid JF, West Jr AP , Walker BD , Seaman MS , Klein F , Nussenzweig MC , Bjorkman PJ
(2022) Sci Adv , 8 , eabp8155 - eabp8155
PUBMED: 35960796
DOI: doi:10.1126/sciadv.abp8155
ISSN: 2375-2548