EMD-26486

Single-particle
2.58 Å
EMD-26486
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Deposition: 24/03/2022
Map released: 18/05/2022
Last modified: 10/07/2024
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EMD-26486
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70S ribosome complex in an intermediate state of translocation bound to EF-G(GDP) stalled by Argyrin B

EMD-26486

Single-particle
2.58 Å
EMD-26486
3D View Gallery
Deposition: 24/03/2022
Map released: 18/05/2022
Last modified: 10/07/2024
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Sample Organism: Escherichia coli, Escherichia coli K-12, Actinoplanes sp.
Sample: 70S ribosome in an intermediate state of translocation bound to EF-G(GDP) and ArgyrinB
Fitted models: 7ug7

Deposition Authors: Rundlet EJ , Wieland M , Holm M, Koller TO , Blanchard SC , Wilson DN
The cyclic octapeptide antibiotic argyrin B inhibits translation by trapping EF-G on the ribosome during translocation.
Wieland M , Holm M, Rundlet EJ , Morici M , Koller TO , Maviza TP , Pogorevc D, Osterman IA , Muller R , Blanchard SC , Wilson DN
(2022) PNAS , 119 , e2114214119 - e2114214119
PUBMED: 35500116
DOI: doi:10.1073/pnas.2114214119
ISSN: 1091-6490
ASTM: PNASA6