EMD-27330

Single-particle
2.8 Å
EMD-27330
3D View Gallery
Deposition: 17/06/2022
Map released: 21/09/2022
Last modified: 12/06/2024
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links

EMD-27330
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8dcx summary report (pdf.gz) Map and 8dcx FULL report (pdf.gz)
EMICSS annotations (xml)

PI 3-kinase alpha with nanobody 3-159

EMD-27330

Single-particle
2.8 Å
EMD-27330
3D View Gallery
Deposition: 17/06/2022
Map released: 21/09/2022
Last modified: 12/06/2024
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Sample Organism: Homo sapiens
Sample: Human PI 3-kinase alpha complex composed of p110alpha and p85alpha with nanobody 3-159 bound
Fitted models: 8dcx

Deposition Authors: Hart JR , Liu X, Pan C, Liang A, Ueno L , Xu Y, Quezada A, Zou X , Yang S, Zhou Q , Schoonooghe S, Hassanzadeh-Ghassabeh G, Xia T, Shui W, Yang D , Vogt PK , Wang M-W
Nanobodies and chemical cross-links advance the structural and functional analysis of PI3K alpha.
Hart JR , Liu X, Pan C, Liang A, Ueno L , Xu Y, Quezada A, Zou X , Yang S, Zhou Q , Schoonooghe S, Hassanzadeh-Ghassabeh G, Xia T, Shui W, Yang D , Vogt PK , Wang MW
(2022) PNAS , 119 , e2210769119 - e2210769119
PUBMED: 36095215
DOI: doi:10.1073/pnas.2210769119
ISSN: 1091-6490
ASTM: PNASA6