EMD-27908

Single-particle
3.3 Å
EMD-27908
3D View Gallery
Deposition: 20/08/2022
Map released: 07/12/2022
Last modified: 21/12/2022
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links

EMD-27908
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3D volume (map.gz) Experimental metadata (xml)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8e5a summary report (pdf.gz) Map and 8e5a FULL report (pdf.gz)
EMICSS annotations (xml)

Human L-type voltage-gated calcium channel Cav1.3 treated with 1.4 mM Sofosbuvir at 3.3 Angstrom resolution

EMD-27908

Single-particle
3.3 Å
EMD-27908
3D View Gallery
Deposition: 20/08/2022
Map released: 07/12/2022
Last modified: 21/12/2022
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Sample Organism: Homo sapiens
Sample: Cav1.3
Fitted models: 8e5a

Deposition Authors: Gao S , Yao X , Yan N
Structural basis for the severe adverse interaction of sofosbuvir and amiodarone on L-type Ca v channels.
Yao X , Gao S , Wang J, Li Z, Huang J , Wang Y, Wang Z, Chen J, Fan X , Wang W, Jin X, Pan X, Yu Y, Lagrutta A, Yan N
(2022) Cell , 185 , 4801 - 4810.e13
PUBMED: 36417914
DOI: doi:10.1016/j.cell.2022.10.024
ISSN: 1097-4172