EMD-29364

Single-particle
3.14 Å
EMD-29364
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Deposition: 04/01/2023
Map released: 28/02/2024
Last modified: 01/05/2024
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links

EMD-29364
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Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8fph summary report (pdf.gz) Map and 8fph FULL report (pdf.gz)
EMICSS annotations (xml)

Conformation 2 of the ligand binding domain (LBDconf2) of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 10mM CaCl2, 150mM NaCl, 1mM MgCl2, 330uM CTZ, and 100mM glutamate (Open-CaNaMg)

EMD-29364

Single-particle
3.14 Å
EMD-29364
3D View Gallery
Deposition: 04/01/2023
Map released: 28/02/2024
Last modified: 01/05/2024
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Sample Organism: Rattus norvegicus
Sample: GluA2 flip-Q isoform in complex with TARP gamma2 (K52E, K53E)
Fitted models: 8fph

Deposition Authors: Nakagawa T
The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nakagawa T , Wang XT , Miguez-Cabello FJ, Bowie D
(2024) Nat Struct Mol Biol , 31 , 688 - 700
PUBMED: 38409505
DOI: doi:10.1038/s41594-024-01228-3
ISSN: 1545-9985