EMD-29700

Single-particle
2.2 Å
EMD-29700
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Deposition: 08/02/2023
Map released: 09/08/2023
Last modified: 27/09/2023
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links

EMD-29700
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3D volume (map.gz) Experimental metadata (xml)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8g3k summary report (pdf.gz) Map and 8g3k FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM imaging scaffold subunits A and B used to display KRAS G12C complex with GDP

EMD-29700

Single-particle
2.2 Å
EMD-29700
3D View Gallery
Deposition: 08/02/2023
Map released: 09/08/2023
Last modified: 27/09/2023
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Sample Organism: synthetic construct, Thermoplasma acidophilum
Sample: Cryo-EM imaging scaffold displaying KRAS G12C
Fitted models: 8g3k

Deposition Authors: Castells-Graells R , Sawaya MR , Yeates TO
Cryo-EM structure determination of small therapeutic protein targets at 3 angstrom -resolution using a rigid imaging scaffold.
Castells-Graells R , Meador K , Arbing MA , Sawaya MR , Gee M , Cascio D , Gleave E, Debreczeni JE, Breed J, Leopold K , Patel A , Jahagirdar D , Lyons B, Subramaniam S , Phillips C , Yeates TO
(2023) PNAS , 120 , e2305494120 - e2305494120
PUBMED: 37669364
DOI: doi:10.1073/pnas.2305494120
ISSN: 1091-6490
ASTM: PNASA6