EMD-29728

Single-particle
3.06 Å
EMD-29728 Deposition: 10/02/2023
Map released: 20/09/2023
Last modified: 15/11/2023
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links

EMD-29728

Native GABA-A receptor from the mouse brain, alpha1-beta2-gamma2 subtype, in complex with didesethylflurazepam and endogenous GABA

EMD-29728

Single-particle
3.06 Å
EMD-29728 Deposition: 10/02/2023
Map released: 20/09/2023
Last modified: 15/11/2023
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Sample Organism: Mus musculus
Sample: Native GABAA Receptor isolated from mouse brain containing two alpha1 subunits, in complex with 8E3-Fab, didesethylflurazepam, and endogenous GABA
Fitted models: 8g4o

Deposition Authors: Sun C , Gouaux E
Cryo-EM structures reveal native GABA A receptor assemblies and pharmacology.
Sun C , Zhu H, Clark S, Gouaux E
(2023) Nature , 622 , 195 - 201
PUBMED: 37730991
DOI: doi:10.1038/s41586-023-06556-w
ISSN: 1476-4687
ASTM: NATUAS