EMD-34871

Single-particle
3.63 Å
EMD-34871
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Deposition: 29/11/2022
Map released: 04/10/2023
Last modified: 04/10/2023
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Overview 3D View Sample Experiment Validation Volume Browser Additional data Links

EMD-34871
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Cryo-EM structure of biparatopic antibody Bp109-92 in complex with TNFR2

EMD-34871

Single-particle
3.63 Å
EMD-34871
3D View Gallery
Deposition: 29/11/2022
Map released: 04/10/2023
Last modified: 04/10/2023
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Sample Organism: Homo sapiens, Escherichia coli (strain K12)
Sample: Cryo-EM structure of biparatopic antibody Bp109-92 in complex with TNFR2
Fitted models: 8hlb

Deposition Authors: Akiba H , Fujita J , Ise T, Nishiyama K , Miyata T , Kato T , Namba K , Ohno H , Kamada H , Nagata S , Tsumoto K
Development of a 1:1-binding biparatopic anti-TNFR2 antagonist by reducing signaling activity through epitope selection.
Akiba H , Fujita J , Ise T, Nishiyama K , Miyata T , Kato T , Namba K , Ohno H , Kamada H , Nagata S , Tsumoto K
(2023) Commun Biol , 6 , 987 - 987
PUBMED: 37758868
DOI: doi:10.1038/s42003-023-05326-8
ISSN: 2399-3642