EMD-40741

Single-particle
3.58 Å
EMD-40741
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Deposition: 08/05/2023
Map released: 06/09/2023
Last modified: 01/11/2023
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Overview 3D View Sample Experiment Validation Volume Browser Additional data Links

EMD-40741
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Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8ss2 summary report (pdf.gz) Map and 8ss2 FULL report (pdf.gz)
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Structure of AMPA receptor GluA2 complex with auxiliary subunits TARP gamma-5 and cornichon-2 bound to competitive antagonist ZK and channel blocker spermidine (closed state)

EMD-40741

Single-particle
3.58 Å
EMD-40741
3D View Gallery
Deposition: 08/05/2023
Map released: 06/09/2023
Last modified: 01/11/2023
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Sample Organism: Rattus norvegicus, Homo sapiens
Sample: GluA2-TARP gamma5-cornichon-2
Fitted models: 8ss2

Deposition Authors: Gangwar SP , Yen LY, Yelshanskaya MV, Sobolevsky AI
Modulation of GluA2-gamma 5 synaptic complex desensitization, polyamine block and antiepileptic perampanel inhibition by auxiliary subunit cornichon-2.
Gangwar SP , Yen LY, Yelshanskaya MV, Korman A , Jones DR , Sobolevsky AI
(2023) Nat Struct Mol Biol , 30 , 1481 - 1494
PUBMED: 37653241
DOI: doi:10.1038/s41594-023-01080-x
ISSN: 1545-9985