EMD-41171

Helical reconstruction
3.1 Å
EMD-41171
3D View Gallery
Deposition: 04/07/2023
Map released: 13/12/2023
Last modified: 13/03/2024
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links

EMD-41171
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8tdn summary report (pdf.gz) Map and 8tdn FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of cardiac amyloid fibril from a variant ATTR I84S amyloidosis patient-3, wild-type morphology

EMD-41171

Helical reconstruction
3.1 Å
EMD-41171
3D View Gallery
Deposition: 04/07/2023
Map released: 13/12/2023
Last modified: 13/03/2024
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Sample Organism: Homo sapiens
Sample: Transthyretin fibrils extracted from patient heart.
Fitted models: 8tdn

Deposition Authors: Nguyen BA , Singh V , Saelices L
Structural polymorphism of amyloid fibrils in ATTR amyloidosis revealed by cryo-electron microscopy.
Nguyen BA , Singh V , Afrin S, Yakubovska A, Wang L, Ahmed Y, Pedretti R, Fernandez-Ramirez MDC, Singh P , Pekala M, Cabrera Hernandez LO , Kumar S, Lemoff A , Gonzalez-Prieto R , Sawaya MR , Eisenberg DS , Benson MD, Saelices L
(2024) Nat Commun , 15 , 581 - 581
PUBMED: 38233397
DOI: doi:10.1038/s41467-024-44820-3
ISSN: 2041-1723