EMD-43683

Single-particle
2.77 Å
EMD-43683
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Deposition: 12/02/2024
Map released: 01/05/2024
Last modified: 22/05/2024
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links

EMD-43683
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8vzn summary report (pdf.gz) Map and 8vzn FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of FLVCR2 in the inward-facing state with choline bound

EMD-43683

Single-particle
2.77 Å
EMD-43683
3D View Gallery
Deposition: 12/02/2024
Map released: 01/05/2024
Last modified: 22/05/2024
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Sample Organism: Mus musculus, synthetic construct
Sample: FLVCR2 in the inward-facing state complexed with choline and Fab FLV9
Fitted models: 8vzn

Deposition Authors: Cater RJ , Mancia F
Structural and molecular basis of choline uptake into the brain by FLVCR2.
Cater RJ , Mukherjee D, Gil-Iturbe E , Erramilli SK , Chen T, Koo K, Santander N , Reckers A , Kloss B, Gawda T , Choy BC, Zhang Z, Katewa A, Larpthaveesarp A, Huang EJ , Mooney SWJ, Clarke OB, Yee SW , Giacomini KM , Kossiakoff AA , Quick M, Arnold T , Mancia F
(2024) Nature , 629 , 704 - 709
PUBMED: 38693257
DOI: doi:10.1038/s41586-024-07326-y
ISSN: 1476-4687
ASTM: NATUAS