EMD-45901

Single-particle
3.5 Å
EMD-45901
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Deposition: 24/07/2024
Map released: 02/10/2024
Last modified: 02/10/2024
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Overview 3D View Sample Experiment Validation Volume Browser Additional data Links

EMD-45901
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Focused refinement of the Heptahelical transmembrane (7TM) domain of the calcium-sensing receptor bound to positive modulator '54149

EMD-45901

Single-particle
3.5 Å
EMD-45901
3D View Gallery
Deposition: 24/07/2024
Map released: 02/10/2024
Last modified: 02/10/2024
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Sample Organism: Homo sapiens
Sample: Calcium-sensing receptor bound to compound '54149

Deposition Authors: Wu C, Skiniotis G
Large library docking identifies positive allosteric modulators of the calcium-sensing receptor.
Liu F , Wu CG , Tu CL, Glenn I , Meyerowitz J , Kaplan AL , Lyu J , Cheng Z, Tarkhanova OO , Moroz YS , Irwin JJ , Chang W , Shoichet BK , Skiniotis G
(2024) Science , 385 , eado1868 - eado1868
PUBMED: 39298584
DOI: doi:10.1126/science.ado1868
ISSN: 1095-9203
ASTM: SCIEAS