EMD-15084

Single-particle
3.6 Å
EMD-15084
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Deposition: 01/06/2022
Map released: 14/06/2023
Last modified: 05/07/2023
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links

EMD-15084
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3D volume (map.gz) Experimental metadata (xml)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8a1r summary report (pdf.gz) Map and 8a1r FULL report (pdf.gz)
EMICSS annotations (xml)

cryo-EM structure of thioredoxin glutathione reductase in complex with a non-competitive inhibitor

EMD-15084

Single-particle
3.6 Å
EMD-15084
3D View Gallery
Deposition: 01/06/2022
Map released: 14/06/2023
Last modified: 05/07/2023
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Sample Organism: Schistosoma mansoni
Sample: TGR in complex with an inhibitor
Fitted models: 8a1r

Deposition Authors: Ardini M , Angelucci F , Fata F , Gabriele F, Effantin G , Ling W, Williams DL , Petukhova VZ, Petukhov PA
Non-covalent inhibitors of thioredoxin glutathione reductase with schistosomicidal activity in vivo.
Petukhova VZ, Aboagye SY , Ardini M , Lullo RP , Fata F , Byrne ME, Gabriele F, Martin LM , Harding LNM , Gone V , Dangi B, Lantvit DD, Nikolic D, Ippoliti R , Effantin G , Ling WL , Johnson JJ, Thatcher GRJ, Angelucci F , Williams DL , Petukhov PA
(2023) Nat Commun , 14 , 3737 - 3737
PUBMED: 37349300
DOI: doi:10.1038/s41467-023-39444-y
ISSN: 2041-1723