EMD-15679

Single-particle
4.42 Å
EMD-15679
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Deposition: 26/08/2022
Map released: 05/04/2023
Last modified: 26/04/2023
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Overview 3D View Sample Experiment Validation Volume Browser Additional data Links

EMD-15679
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Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8avd summary report (pdf.gz) Map and 8avd FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure for a 3:3 complex between mouse leptin and the mouse LEP-R ectodomain (local refinement)

EMD-15679

Single-particle
4.42 Å
EMD-15679
3D View Gallery
Deposition: 26/08/2022
Map released: 05/04/2023
Last modified: 26/04/2023
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Sample Organism: Mus musculus
Sample: Stucture of mouse leptin in complex with a trimerized form of the mouse Lep-R extracellular region
Fitted models: 8avd

Deposition Authors: Verstraete K , Savvides SN , Verschueren KG , Tsirigotaki A
Mechanism of receptor assembly via the pleiotropic adipokine Leptin.
Tsirigotaki A , Dansercoer A, Verschueren KHG, Markovic I , Pollmann C , Hafer M, Felix J , Birck C , Van Putte W , Catteeuw D, Tavernier J , Fernando Bazan J, Piehler J , Savvides SN , Verstraete K
(2023) Nat Struct Mol Biol , 30 , 551 - 563
PUBMED: 36959263
DOI: doi:10.1038/s41594-023-00941-9
ISSN: 1545-9985