EMD-18657

Single-particle
3.5 Å
EMD-18657
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Deposition: 14/10/2023
Map released: 06/12/2023
Last modified: 24/01/2024
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links

EMD-18657
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8qu8 summary report (pdf.gz) Map and 8qu8 FULL report (pdf.gz)
EMICSS annotations (xml)

PROTAC-mediated complex of KRAS with VHL/Elongin-B/Elongin-C/Cullin-2/Rbx1

EMD-18657

Single-particle
3.5 Å
EMD-18657
3D View Gallery
Deposition: 14/10/2023
Map released: 06/12/2023
Last modified: 24/01/2024
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Sample Organism: Homo sapiens
Sample: KRAS/ACBI3/VHL/EloB/EloC/Cul2/Rbx1
Fitted models: 8qu8

Deposition Authors: Fischer G, Peter D, Arce-Solano S
Targeting cancer with small molecule pan-KRAS degraders
Popow J, Farnaby W, Gollner A, Kofink C, Fischer G, Wurm M, Zollman D, Wijaya A, Mischerikow N, Hasenoehrl C, Prokofeva P, Arnhof H, Arce-Solano S, Bell S, Boeck G, Diers E, Frost A, Goodwin-Tindall J, Karolyi-Oezguer J, Khan S, Klawatsch T, Koegl M, Kousek R, Kratochvil B, Kropatsch K, Lauber A, McLennan R, Olt S, Peter D, Petermann O, Roessler V, Stolt-Bergner P, Strack P, Strauss E, Trainor N, Vetma V, Whitworth C, Zhong S, Quant J, Weinstabl H, Kuster B, Ettmayer P, Ciulli A
(2023) bioRxiv
DOI: doi:10.1101/2023.10.24.563163
ISSN: 2692-8205