EMD-20901

Single-particle
2.4 Å
EMD-20901
3D View Gallery
Deposition: 31/10/2019
Map released: 01/04/2020
Last modified: 25/11/2020
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links

EMD-20901
Download
3D volume (map.gz) Experimental metadata (xml)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 6uus summary report (pdf.gz) Map and 6uus FULL report (pdf.gz)
EMICSS annotations (xml)

CryoEM Structure of the active Adrenomedullin 2 receptor G protein complex with adrenomedullin peptide

EMD-20901

Single-particle
2.4 Å
EMD-20901
3D View Gallery
Deposition: 31/10/2019
Map released: 01/04/2020
Last modified: 25/11/2020
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Sample Organism: Homo sapiens, Lama glama
Sample: AM2:CLR:RAMP3:GasDN:Gb1:Gg2:Nb35 GPCR Complex
Fitted models: 6uus

Deposition Authors: Belousoff MJ, Liang YL, Sexton P, Danev R
Structure and Dynamics of Adrenomedullin Receptors AM1and AM2Reveal Key Mechanisms in the Control of Receptor Phenotype by Receptor Activity-Modifying Proteins.
Liang YL, Belousoff MJ , Fletcher MM , Zhang X , Khoshouei M, Deganutti G , Koole C, Furness SGB , Miller LJ, Hay DL , Christopoulos A, Reynolds CA , Danev R, Wootten D , Sexton PM
(2020) Acs Pharmacol Transl Sci , 3 , 263 - 284
PUBMED: 32296767
DOI: doi:10.1021/acsptsci.9b00080
ISSN: 2575-910